(+)-MAGNOFLORINE IODIDE
- CAS No.
- 2141-09-5
- Chemical Name:
- (+)-MAGNOFLORINE IODIDE
- Synonyms
- escholin;Esholine;escholine;THALICTRIN;Aids002649;Magflorine;THALICTRINE;Aids-002649;MAGNOFLORINE;(+)-Magnoflorine
- CBNumber:
- CB0350572
- Molecular Formula:
- C20H24INO4
- Molecular Weight:
- 469.31
- MDL Number:
- MFCD03427294
- MOL File:
- 2141-09-5.mol
- MSDS File:
- SDS
| Melting point | 252℃ |
|---|---|
| storage temp. | 2-8°C(protect from light) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| FDA UNII | NI8K6962K4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H341 | |||||||||
| Precautionary statements | P501-P202-P201-P264-P280-P302+P352-P308+P313-P337+P313-P305+P351+P338-P362+P364-P332+P313-P405 | |||||||||
| NFPA 704 |
|
(+)-MAGNOFLORINE IODIDE price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25122 | Magnoflorine ≥98% | 2141-09-5 | 5mg | $97 | 2024-03-01 | Buy |
| Cayman Chemical | 25122 | Magnoflorine ≥98% | 2141-09-5 | 10mg | $145 | 2024-03-01 | Buy |
| Cayman Chemical | 25122 | Magnoflorine ≥98% | 2141-09-5 | 25mg | $337 | 2024-03-01 | Buy |
| Cayman Chemical | 25122 | Magnoflorine ≥98% | 2141-09-5 | 50mg | $625 | 2024-03-01 | Buy |
| Usbiological | 300608 | Magnoflorine Iodide | 2141-09-5 | 10mg | $448 | 2021-12-16 | Buy |
(+)-MAGNOFLORINE IODIDE Chemical Properties,Uses,Production
Description
A wide variety of species contain this quaternary alkaloid which is widespread among the families, Aquilegia, Magnolia and Michelia. It has been isolated and characterized as the iodide, m.p. 248-9°C (dec.); [0:11>5 + 200.1° (MeOH). The optically inactive base also yields an iodide which crystallizes with 1.5 H20, m.p. 243°C (dec.).
Description
Magnoflorine is an alkaloid and a major constituent of S. acutum that has diverse biological activities. It reduces hemolysis induced by lysophosphatidylcholine (LPC), but not NaCl, in a rat erythrocyte suspension when used at concentrations ranging from 0.01 to 10 μM. Magnoflorine (10 μM) induces intracellular chloride influx in neuroblastoma cells, an effect that is reversed by the GABAA receptor antagonist bicuculline . It reduces TNF-α-induced NF-κB expression as well as production of IL-6 and IL-8 in BEAS-2B cells. In vivo, magnoflorine (20 mg/kg, i.p.) improves short- and long-term memory acquisition in a passive avoidance test in a mouse model of scopolamine-induced memory impairment.
Uses
Magnoflorine-d3 is the labelled analogue of Magnoflorine, an isoquinoline alkaloid from the Coptis japonica and it enhances the myoblast differentiation through activation of the p38 MAP kinase and Akt pathway.
Definition
ChEBI: (S)-magnoflorine is an aporphine alkaloid that is (S)-corytuberine in which the nitrogen has been quaternised by an additional methyl group. It has a role as a plant metabolite. It is an aporphine alkaloid and a quaternary ammonium ion. It is functionally related to a (S)-corytuberine.
References
Nakano., Chem. Pharm. Bull. (Tokyo), 2, 329 (1954) Tomita, Kikkawa.,J. Pharm. Soc., Japan, 77, 195 (1957) Gopinath et aI., J. Sci. Ind. Res., 18B, 444 (1959) Ishii, Harada.,J. Pharm. Soc., Japan, 81,238 (1961) Yang, Lu, Hsiao., ibid, 82,794,816 (1962) Yang, Lu, Hsiao., ibid, 83,216 (1963)
(+)-MAGNOFLORINE IODIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from (+)-MAGNOFLORINE IODIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | magnoflorine
2141-09-5
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2023-02-24 | Magnoflorine
2141-09-5
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2019-07-14 | (+)-MAGNOFLORINE IODIDE
2141-09-5
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
-
- magnoflorine
2141-09-5
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Magnoflorine
2141-09-5
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- (+)-MAGNOFLORINE IODIDE
2141-09-5
- US $1.00 / KG
- 99%
- Career Henan Chemical Co