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KEA1-97

CAS No.
2138882-71-8
Chemical Name:
KEA1-97
Synonyms
KEA1-97;KEA1-97 >=98% (HPLC);4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-;Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197
CBNumber:
CB04668109
Molecular Formula:
C15H9Cl2FN4
Molecular Weight:
335.16
MDL Number:
MFCD31697744
MOL File:
2138882-71-8.mol
Last updated:2023-09-20 16:43:00

KEA1-97 Properties

Boiling point 530.3±52.0 °C(Predicted)
Density 1.466±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility DMSO : 100 mg/mL (298.36 mM; Need ultrasonic)
pka 0.57±0.10(Predicted)

KEA1-97 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2180 KEA1-97 ≥98% (HPLC) 2138882-71-8 5mg $102 2024-03-01 Buy
Sigma-Aldrich SML2180 KEA1-97 ≥98% (HPLC) 2138882-71-8 25mg $329 2024-03-01 Buy
Product number Packaging Price Buy
SML2180 5mg $102 Buy
SML2180 25mg $329 Buy

KEA1-97 Chemical Properties,Uses,Production

Description

KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 and inducing apoptosis without affecting other thioredoxin activity. KEA1-97 induced apoptosis in breast cancer cells and treatment of immune-deficient SCID mice at 5 mg/kg ip impaired breast tumor xenograft growth.

KEA1-97 Preparation Products And Raw materials

Raw materials

Preparation Products

KEA1-97 Suppliers

Global( 27)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 chaolaichem@foxmail.com China 7565 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4121 55
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8011 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2982 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9445 58
Shanghai Dongyang Biotechnology Co., Ltd. 0512-0512-13601744364 13601744364 chemsharker@126.com China 879 58

KEA1-97 Spectrum

KEA1-97 1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)- KEA1-97 >=98% (HPLC) 4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197 4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine 2138882-71-8 C15H9Cl2FN4