Anti-GFAP antibody, Rabbit monoclonal

CAS No.
Chemical Name:
Anti-GFAP antibody, Rabbit monoclonal
Synonyms
Anti-GFAP antibody, Rabbit monoclonal
CBNumber:
CB04669252
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Anti-GFAP antibody, Rabbit monoclonal Properties

storage temp. -20°C

Anti-GFAP antibody, Rabbit monoclonal price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB5500113 Anti-GFAP antibody, Rabbit monoclonal clone SP78, recombinant, expressed in proprietary host, affinity isolated antibody 100μL $338 2024-03-01 Buy
Product number Packaging Price Buy
SAB5500113 100μL $338 Buy

Anti-GFAP antibody, Rabbit monoclonal Chemical Properties,Uses,Production

Uses

Anti-GFAP antibody, Rabbit monoclonal has been used in immunocytochemistry and Immunohistochemistry.

General Description

Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition, many types of brain tumors presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is particular expressed in auricular chondrocytes.

Biochem/physiol Actions

Glial fibrillary acidic protein (GFAP) maintains the structure and motility of astrocytes. Gfap mediates the interaction between neurons and glial cells. It is responsible for the integrity and function of blood-brain barrier. Myelination and brain injury induced astrogliosis is controlled by Gfap. Cytoskeleton disintegration is known to stimulate the release of Gfap. Upregulation of this gene is observed in traumatic brain injury such as intracerebral hemorrhage and thus serves as a biomarker. Mutation in the GFAP gene causes Alexander disease.

Anti-GFAP antibody, Rabbit monoclonal Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-GFAP antibody, Rabbit monoclonal Suppliers

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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
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Anti-GFAP antibody, Rabbit monoclonal