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ChemicalBook >> CAS DataBase List >>S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Structure
S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O structure
CAS No.
5653-80-5
Chemical Name:
S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O
Synonyms
d-methadone;6s-methadone;S-(+)-Methadone;l-(+)-methadone;dextromethadone;4-diphenyl-6-(dimethylamino)-(s)-3-heptanon;d-6-(dimethylamino)-4,4-diphenyl-3-heptanone;(s)-6-(dimethylamino)-4,4-diphenyl-3-heptanone;(6S)-6-(diMethylaMino)-4,4-diphenylheptan-3-one;3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (6S)-
CBNumber:
CB0498241
Molecular Formula:
C21H27NO
Molecular Weight:
309.45
MDL Number:
MFCD00151717
MOL File:
5653-80-5.mol
Last updated:2023-05-15 10:43:19

S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Properties

Melting point 100.5°C
Boiling point 449.71°C (rough estimate)
Density 1.0350 (rough estimate)
refractive index 1.5614 (estimate)
solubility H2O: soluble
form solid
pka 9.05±0.50(Predicted)
color white
FDA UNII S95RZH8AMH

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS06
Signal word  Danger
Hazard statements  H335-H334-H301-H319-H315-H317
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P310-P321-P330-P405-P501-P261-P285-P304+P341-P342+P311-P501-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xn
Risk Statements  22-36/37/38-42/43
Safety Statements  22-26-36/37/39-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  MJ6000000
Toxicity LD50 oral in mouse: 252mg/kg

S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Chemical Properties,Uses,Production

Uses

Dextromethadone-D3 is an impurity of Dextromethadone (CAS #: 5653-80-5). Dextromethadone is used in therapy for treating or preventing depression or other mood diseases.

Definition

ChEBI: Dextromethadone is a 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder. It has a role as a NMDA receptor antagonist and an opioid analgesic. It is an enantiomer of a levomethadone.

S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Preparation Products And Raw materials

Raw materials

Preparation Products

5653-80-5(S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O)Related Search:

Methadone hydrochloride
(6S)-6-(diMethylaMino)-4,4-diphenylheptan-3-one S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O (s)-6-(dimethylamino)-4,4-diphenyl-3-heptanone 4-diphenyl-6-(dimethylamino)-(s)-3-heptanon 6s-methadone d-6-(dimethylamino)-4,4-diphenyl-3-heptanone dextromethadone d-methadone l-(+)-methadone S-(+)-Methadone 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (6S)- 5653-80-5