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METHANTHELINE BROMIDE

CAS No.
53-46-3
Chemical Name:
METHANTHELINE BROMIDE
Synonyms
mtb51;sc2910;ulcine;avagal;metaxan;vagamin;banthin;asabaine;Bantosal;metantyl
CBNumber:
CB0501370
Molecular Formula:
CH3-
Molecular Weight:
15.03452
MDL Number:
MFCD00031733
MOL File:
53-46-3.mol
Last updated:2023-05-04 17:34:39

METHANTHELINE BROMIDE Properties

Melting point 175-176°
Density 1.3380 (rough estimate)
refractive index 1.6200 (estimate)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
color Dark Orange to Very Dark Orange
FDA UNII 090519SAPF
ATC code A03AB07

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H332
Precautionary statements  P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312
Toxicity LD50 i.p. in mice: 76 mg/kg (Hambourger)

METHANTHELINE BROMIDE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC U700650 UlcineBromide 53-46-3 50mg $180 2021-12-16 Buy
American Custom Chemicals Corporation API0028335 METHANTHELINE BROMIDE 95.00% 53-46-3 5MG $497.29 2021-12-16 Buy
Medical Isotopes, Inc. 49170 UlcineBromide 53-46-3 50mg $650 2021-12-16 Buy
Product number Packaging Price Buy
U700650 50mg $180 Buy
API0028335 5MG $497.29 Buy
49170 50mg $650 Buy

METHANTHELINE BROMIDE Chemical Properties,Uses,Production

Uses

Ulcine is a strong muscarinic receptor blocking drug used in the treatment of overactive bladder syndrome, hypersalivation and hyperhidrosis.

Uses

METHANTHELINE BROMIDE is a strong muscarinic receptor blocking drug used in the treatment of overactive bladder syndrome, hypersalivation and hyperhidrosis.

Definition

ChEBI: Methantheline bromide is a member of xanthenes.

General Description

Methanthelinebromide, diethyl(2-hydroxyethyl)methylammonium bromidexanthene-9-carboxylate (Banthine Bromide), is awhite, slightly hygroscopic, crystalline salt that is solublein water to produce solutions with a pH of about 5.Aqueous solutions are not stable and hydrolyze in a fewdays. The bromide form is preferable to the very hygroscopicchloride.
Among the conditions for which methantheline bromideis indicated are gastritis, intestinal hypermotility, bladderirritability, cholinergic spasm, pancreatitis, hyperhidrosis,and peptic ulcer, all of which are manifestations ofparasympathotonia.

Clinical Use

Methantheline bromide, introduced in 1950, is a potent anticholinergicagent and acts at the nicotinic cholinergic receptors of thesympathetic and parasympathetic systems, as well as at themyoneural junction of the postganglionic cholinergic fibers.Like other quaternary ammonium drugs, methantheline bromideis absorbed incompletely from the GI tract.

METHANTHELINE BROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ammonium,diethyl(2-hydroxyethyl)methyl-,bromide,xanthene-9-carboxylate asabaine METHANETHELINIUMBROMIDE Bantosal frenogastrico gastrosedan mantheline metantyl metaxan methanide methanthelinebromide methantheliniumbromide methanthinebromide methelina mtb51 n,n-diethyl-n-methyl-2-((9h-xanthen-9-ylcarbonyl)oxy)-ethanaminiubromide resobantin sc2910 ulcine ulcudexter vagamin vagantin xanteline xanthene-9-carboxylicacid,esterwithdiethyl(2-hydroxyethyl)methylammonium METHANTHELINE BROMIDE (200 MG) Methantheline avagal banthin banthine banthinebromide beta-diethylaminoethyl9-xanthenecarboxylatemethobromide beta-diethylaminoethylxanthene-9-carboxylatemethobromide diethyl(2-hydroxyethyl)methylammoniumbromidexanthene-9-carboxylate doladene diethyl-methyl-[2-(9H-xanthen-9-ylcarbonyloxy)ethyl]azanium bromide diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]ammonium bromide diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium bromide Ulcine Bromide Methantheline Bromide (1401001) Dixamone bromide 53-46-3 C21H26NO3Br