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N-Desthiobiotin-N-bis(PEG4-NHS ester)

CAS No.
2353409-61-5
Chemical Name:
N-Desthiobiotin-N-bis(PEG4-NHS ester)
Synonyms
N-Desthiobiotin-N-bis(PEG4-NHS ester);4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[6-[(4R,5S)-5-methyl-2-oxo-4-imidazolidinyl]-1-oxohexyl]-, 1,31-bis(2,5-dioxo-1-pyrrolidinyl) ester
CBNumber:
CB05852006
Molecular Formula:
C40H65N5O18
Molecular Weight:
903.97
MDL Number:
MFCD31811455
MOL File:
2353409-61-5.mol
Last updated:2025-04-18 09:51:34
Product description Number Pack Size Price
N-Desthiobiotin-N-bis(PEG4-NHSester) 95% BP-24278 50mg $350
N-Desthiobiotin-N-bis(PEG4-NHSester) 95% BP-24278 100mg $650

N-Desthiobiotin-N-bis(PEG4-NHS ester) Properties

Density 1.30±0.1 g/cm3(Predicted)
pka 14.94±0.60(Predicted)

N-Desthiobiotin-N-bis(PEG4-NHS ester) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-24278 N-Desthiobiotin-N-bis(PEG4-NHSester) 95% 2353409-61-5 50mg $350 2021-12-16 Buy
BroadPharm BP-24278 N-Desthiobiotin-N-bis(PEG4-NHSester) 95% 2353409-61-5 100mg $650 2021-12-16 Buy
Product number Packaging Price Buy
BP-24278 50mg $350 Buy
BP-24278 100mg $650 Buy

N-Desthiobiotin-N-bis(PEG4-NHS ester) Chemical Properties,Uses,Production

Description

N-Desthiobiotin-N-bis(PEG4-NHS ester) is a PEG linker containing two NHS esters groups and desthiobiotin, which is a modified form of biotin that bonds to avidin, streptavidin and other biotin-binding protein-based affinity columns and are recognized by anti-biotin antibodies. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

N-Desthiobiotin-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-Desthiobiotin-N-bis(PEG4-NHS ester) Preparation Products And Raw materials

Raw materials

Preparation Products

N-Desthiobiotin-N-bis(PEG4-NHS ester) Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 1924344760@confluore.cn China 2997 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4952 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85563444 18351873721 purchase@synzest.com China 10434 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 3001317055@qq.com China 9682 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29757 58
Affinity(Wuhan)Ltd. 15841022315 sales@affinitytech.cn China 3000 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58

View Lastest Price from N-Desthiobiotin-N-bis(PEG4-NHS ester) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Desthiobiotin-N-bis(PEG4-NHS ester) pictures 2025-06-07 N-Desthiobiotin-N-bis(PEG4-NHS ester)
2353409-61-5
US $0.00 / mg 100mg >95.00% 100mg Xian confluore Biological Technology Co., Ltd.
4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[6-[(4R,5S)-5-methyl-2-oxo-4-imidazolidinyl]-1-oxohexyl]-, 1,31-bis(2,5-dioxo-1-pyrrolidinyl) ester N-Desthiobiotin-N-bis(PEG4-NHS ester) 2353409-61-5 C40H65N5O18