ANTI-H2AX (PSER139) RABBIT PAB
- CAS No.
- Chemical Name:
- ANTI-H2AX (PSER139) RABBIT PAB
- Synonyms
- Anti-H2AXS139p;ANTI-H2AX (PSER139) RABBIT PAB;ANTI-PHOSPHO-HISTONE H2AX [PSER139];Anti-phospho-Histone H2AX (pSer139) antibody produced in rabbit
- CBNumber:
- CB0765132
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD04974783
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
Safety Statements | 23-24/25 |
---|---|
WGK Germany | 2 |
ANTI-H2AX (PSER139) RABBIT PAB price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SAB4504428 | Anti-phospho-Histone H2A.X (pSer139) antibody produced in rabbit affinity isolated antibody | 100μG | $506 | 2024-03-01 | Buy | |
Sigma-Aldrich | H5912 | Anti-phospho-Histone H2AX (pSer139) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 200μL | $361.8 | 2024-03-01 | Buy |
ANTI-H2AX (PSER139) RABBIT PAB Chemical Properties,Uses,Production
Uses
Anti-phospho-Histone H2AX (pSer139) antibody produced in rabbit has been used in immunofluorescence and western blotting.
General Description
H2AX comprises 2-25% of the total H2A complement in human cells, whereas in the budding yeast it constitutes virtually all of the H2A molecules. It has N-terminal and C-terminal region with a central globular domain. The C-terminal region has sites for modification including acetylation, biotinylation and phosphorylation.
Biochem/physiol Actions
H2AX is critical for facilitating the assembly of specific DNA-repair complexes on damaged DNA. Ataxia-telangiectasia-mutated (ATM) is the major kinase involved in the phosphorylation of H2AX in response to DNA double-strand breaks. H2AX knockout mice are radiation sensitive and show retarted growth. They also are immune deficient with mutant males are infertile..
ANTI-H2AX (PSER139) RABBIT PAB Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-H2AX (PSER139) RABBIT PAB Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |