ANTI-PRO-BDNF
- CAS No.
- Chemical Name:
- ANTI-PRO-BDNF
- Synonyms
- ANTI-PRO-BDNF;ANTI-PRO-BRAIN-DERIVED NEUROTROPHIC FACTOR;Anti-Pro-BDNF antibody produced in rabbit
- CBNumber:
- CB0822325
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD08705507
- MOL File:
- Mol file
ANTI-PRO-BDNF Chemical Properties,Uses,Production
Uses
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
General Description
The brain derived neurotrophic factor (BDNF) gene is mapped to human chromosome 11p14.1. The gene encodes a precursor protein, proBDNF. Mature BDNF (mBDNF) is synthesized by post-translational cleavage of proBDNF. Does not cross react with pro-NGF, pro-NT-3, or mature BDNF.
Biochem/physiol Actions
Brain derived neurotrophic factor (BDNF) belongs to a family of secreted proteins called neurotrophins. Neurotrophins are synthesized as preproneurotrophin precursors and further processed to proneurotrophins and subsequently to neurotrophins. BDNF is expressed in the developing and the mature brain. The influence of BDNF is mediated by its binding to TrkB receptor and sometimes the receptor p75NTR. The downstream pathways promoted by BDNF include PI3K, MAPK and JAK/STAT. The most important role of BDNF is the regulation of synaptic transmission and plasticity, protein synthesis and phosphorylation of local proteins.
ANTI-PRO-BDNF Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-PRO-BDNF Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |