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ChemicalBook >> CAS DataBase List >>Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)-

Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)-

Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)- Structure
Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)- structure
CAS No.
177947-03-4
Chemical Name:
Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)-
Synonyms
L772;L 772;L-772;L-772,405;L772,405,L 772,405;Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)-
CBNumber:
CB08860712
Molecular Formula:
C26H31FN6O
Molecular Weight:
462.57
MDL Number:
MFCD19105471
MOL File:
177947-03-4.mol
Last updated:2025-08-21 16:37:02
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Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)- Properties

Boiling point 706.3±70.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
pka 14.44±0.10(Predicted)

Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)- Chemical Properties,Uses,Production

Description

L-772,405 is a highly selective h5-HT(1D) receptor agonists.

Uses

L-772405 is a selective 5-HT1D receptor agonist with the Ki values of 318, 29 and ＞ 1000 nM aganist guinea pig 5-HT1B receptor, guinea pig 5-HT1D receptor and rat 5-HT rransporter, respectively. L-772405 decreases the potassium-induced outflow of 5-HT with an IC50 value of 240 nM[1].

References

[1] Pullar IA, et al. The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig. Eur J Pharmacol. 2004 Jun 16;493(1-3):85-93. DOI:10.1016/j.ejphar.2004.04.029

Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)- Suppliers

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TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19962 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29573 58
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View Lastest Price from Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-772,405 pictures 2025-08-21 L-772,405
177947-03-4
 US $2380.00-3100.00 / mg 10g TargetMol Chemicals Inc.
  • L-772,405 pictures
  • L-772,405
    177947-03-4
  • US $2380.00-3100.00 / mg
  • TargetMol Chemicals Inc.
Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)- L 772 L772 L-772 L-772,405 L772,405,L 772,405 177947-03-4 C26H31FN6O