ChemicalBook >> CAS DataBase List >>Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester

Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester

Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester structure

CAS No.: 1706528-83-7

Chemical Name:: Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester

Synonyms: INS-1009;Treprostinil palmitil;Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester

CBNumber:: CB09752805

Molecular Formula:: C39H66O5

Molecular Weight:: 614.94

MDL Number:

MOL File:: 1706528-83-7.mol

Last updated:2025-04-18 09:51:32

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Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester Properties

Boiling point	705.7±60.0 °C(Predicted)
Density	1.007±0.06 g/cm3(Predicted)
storage temp.	4°C, away from moisture and light
solubility	DMSO : 200 mg/mL (325.23 mM; Need ultrasonic)
form	Solid
pka	15.09±0.40(Predicted)
color	Off-white to light yellow
FDA UNII	8GJK87S89F

Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester Chemical Properties,Uses,Production

Uses

Treprostinil palmitil (TP) is the proagent of DP1 and EP2 agonist, Treprostinil (UT-15), whose EC50 values were 0.6 and 6.2 nM, respectively. Treprostinil palmitil is a pure proagent and possesses no inherent binding to G-protein coupled receptors including prostanoid receptors[1][2].

IC 50

References

[1] Chapman RW, Corboz MR, Malinin VS, Plaunt AJ, Konicek DM, Li Z, Perkins WR. An overview of the biology of a long-acting inhaled treprostinil prodrug. Pulm Pharmacol Ther. 2020 Dec;65:102002. DOI:10.1016/j.pupt.2021.102002

Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9835	58

Supplier	Advantage
RD International Technology Co., Limited	58

Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, hexadecyl ester INS-1009 Treprostinil palmitil 1706528-83-7