1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT
![1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT Structure](CAS/GIF/168021-79-2.gif)
- CAS No.
- 168021-79-2
- Chemical Name:
- 1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT
- Synonyms
- CPI22;D03875;HPN-07;CS-791;CPI 22;CPI-22;CXY059;OKN007;CXY 059;CXY-059
- CBNumber:
- CB11009515
- Molecular Formula:
- C11H14NNa2O7S2
- Molecular Weight:
- 382.3409
- MDL Number:
- MFCD09833648
- MOL File:
- 168021-79-2.mol
- MSDS File:
- SDS
| Melting point | >300 °C |
|---|---|
| storage temp. | -20°C |
| solubility | Soluble in DMSO |
| form | powder |
| color | white to beige |
| FDA UNII | 7M1J3HN9VO |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2163 | HPN-07 ≥98% (HPLC) | 168021-79-2 | 5mg | $64.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2163 | HPN-07 ≥98% (HPLC) | 168021-79-2 | 25mg | $264 | 2024-03-01 | Buy |
| Cayman Chemical | 22109 | NXY-059 ≥98% | 168021-79-2 | 5mg | $48 | 2024-03-01 | Buy |
| Cayman Chemical | 22109 | NXY-059 ≥98% | 168021-79-2 | 10mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 22109 | NXY-059 ≥98% | 168021-79-2 | 25mg | $176 | 2024-03-01 | Buy |
1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT Chemical Properties,Uses,Production
Uses
Cerovive (NXY-059) is a novel nitrone, shows efficacious neuroprotective effects that prevents ischemic damage by trapping free radicals. Used as a spin-trap agent. It is a clinically tested antioxidant and depicts potency against Ischemic stress, Neuroprotection.
Uses
A free radical trapping compound
Uses
Cerovive (NXY-059) is a novel nitrone, shows efficacious neuroprotective effects that prevents ischemic damage by trapping free radicals. Neuroprotectant.
Biological Activity
Free radical trapping agent. Reduces infarct size and preserves brain function in several animal models of acute ischemic stroke. Neuroprotectant.
Biochem/physiol Actions
Originally characterized for its NO-mimicking activity in preventing peroxynitrite formation and in vivo neuroprotective efficacy in animal models of cerebral ischemia (100 mg/kg i.v. in rabbits; 30-60 mg/kg plus 30-60 mg/kg/h i.v. or 50 mg/kg plus 8.8 mg/kg/h s.c. in rats; 28 mg/kg plus 16 mg/kg/h i.v. in monkeys), OKN-007 (HPN-07, NXY-059) is an orally available α-phenyl-tert-butylnitrone (PBN) derivative that is also shown to exhibit sulfatase 2 (SULF2) inhibitory activity and anticancer efficacy both in cultures (effective conc. 170-200 μM in Huh7 heptoma cultures) and in several rodent glioma models in vivo (C6, RG2, and GL261; 75 mg/kg/day for rats and 168 mg/kg/day for mice via drinking water).
References
[1] kuroda s1, tsuchidate r, smith ml, maples kr, siesjö bk.
1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |