1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT
![1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT Structure](CAS/GIF/168021-79-2.gif)
- CAS No.
- 168021-79-2
- Chemical Name:
- 1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT
- Synonyms
- CPI22;D03875;HPN-07;CS-791;CPI 22;CPI-22;CXY059;OKN007;CXY 059;CXY-059
- CBNumber:
- CB11009515
- Molecular Formula:
- C11H14NNa2O7S2
- Molecular Weight:
- 382.3409
- MDL Number:
- MFCD09833648
- MOL File:
- 168021-79-2.mol
- MSDS File:
- SDS
| Melting point | >300 °C |
|---|---|
| storage temp. | -20°C |
| solubility | Soluble in DMSO |
| form | powder |
| color | white to beige |
| Water Solubility | H2O: 2mg/mL, clear |
| FDA UNII | 7M1J3HN9VO |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2163 | HPN-07 ≥98% (HPLC) | 168021-79-2 | 5mg | $64.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2163 | HPN-07 ≥98% (HPLC) | 168021-79-2 | 25mg | $264 | 2024-03-01 | Buy |
| Cayman Chemical | 22109 | NXY-059 ≥98% | 168021-79-2 | 5mg | $48 | 2024-03-01 | Buy |
| Cayman Chemical | 22109 | NXY-059 ≥98% | 168021-79-2 | 10mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 22109 | NXY-059 ≥98% | 168021-79-2 | 25mg | $176 | 2024-03-01 | Buy |
1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT Chemical Properties,Uses,Production
Uses
Cerovive (NXY-059) is a novel nitrone, shows efficacious neuroprotective effects that prevents ischemic damage by trapping free radicals. Used as a spin-trap agent. It is a clinically tested antioxidant and depicts potency against Ischemic stress, Neuroprotection.
Uses
A free radical trapping compound
Biological Activity
Free radical trapping agent. Reduces infarct size and preserves brain function in several animal models of acute ischemic stroke. Neuroprotectant.
Biochem/physiol Actions
Originally characterized for its NO-mimicking activity in preventing peroxynitrite formation and in vivo neuroprotective efficacy in animal models of cerebral ischemia (100 mg/kg i.v. in rabbits; 30-60 mg/kg plus 30-60 mg/kg/h i.v. or 50 mg/kg plus 8.8 mg/kg/h s.c. in rats; 28 mg/kg plus 16 mg/kg/h i.v. in monkeys), OKN-007 (HPN-07, NXY-059) is an orally available α-phenyl-tert-butylnitrone (PBN) derivative that is also shown to exhibit sulfatase 2 (SULF2) inhibitory activity and anticancer efficacy both in cultures (effective conc. 170-200 μM in Huh7 heptoma cultures) and in several rodent glioma models in vivo (C6, RG2, and GL261; 75 mg/kg/day for rats and 168 mg/kg/day for mice via drinking water).
in vivo
Disufenton sodium (28 mg/kg, iv and osmotic pump for 48 h) reduces cerebral infarction volume and improves behavioral dysfunction in marmoset permanent middle cerebral artery occlusion (pMCAO) models[2].
| Animal Model: | Marmoset pMCAO models[2] |
| Dosage: | 60 mg/kg |
| Administration: | 28 mg/kg for iv, 16 mg/kg?h for 48 h via osmotic pump |
| Result: | Ameliorated ischemic brain injury. |
References
[1] kuroda s1, tsuchidate r, smith ml, maples kr, siesjö bk.
1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32239 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38648 | 58 | |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49984 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from 1,3-BENZENEDISULFONIC ACID, 4-[[(1,1-DIMETHYLETHYL)OXIDOIMINO]METHYL]-,DISODIUM SALT manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-28 | Disufenton sodium
168021-79-2
|
US $37.00-118.00 / mg | 98.66% | 10g | TargetMol Chemicals Inc. |
-
- Disufenton sodium
168021-79-2
- US $37.00-118.00 / mg
- 98.66%
- TargetMol Chemicals Inc.