ChemicalBook >> CAS DataBase List >>3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 5-acetyl-4,5,6,7-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, [[(1-ethylpropoxy)carbonyl]oxy]methyl ester, hydrochloride (1:1)
3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 5-acetyl-4,5,6,7-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, [[(1-ethylpropoxy)carbonyl]oxy]methyl ester, hydrochloride (1:1)
- CAS No.
- 190602-72-3
- Chemical Name:
- 3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 5-acetyl-4,5,6,7-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, [[(1-ethylpropoxy)carbonyl]oxy]methyl ester, hydrochloride (1:1)
- Synonyms
- TA-606 free;3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 5-acetyl-4,5,6,7-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, [[(1-ethylpropoxy)carbonyl]oxy]methyl ester, hydrochloride (1:1)
- CBNumber:
- CB110338888
- Molecular Formula:
- C33H40ClN7O6
- Molecular Weight:
- 666.18
- MDL Number:
- MOL File:
- 190602-72-3.mol
Last updated:2023-03-31 09:12:57
3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 5-acetyl-4,5,6,7-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, [[(1-ethylpropoxy)carbonyl]oxy]methyl ester, hydrochloride (1:1) Chemical Properties,Uses,Production
Description
TA-606, also known as TA-606 free, is an angiotensin type 1 receptor antagonist potentially for the treatment of hypertension. TA-606 was immediately converted to its active form, 606A, after oral administration, and it demonstrated potent inhibition of the Ang II-induced pressor response in conscious normotensive dogs. It also had a potent hypotensive effect in conscious 2K,1C-renal hypertensive dogs. These effects of TA-606 were 32 and 30 times more potent than those of losartan, respectively. In addition, EXP3174, an active metabolite of losartan, but not 606A showed an orthostatic hypotensive effect in the rat tilting model.
3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 5-acetyl-4,5,6,7-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, [[(1-ethylpropoxy)carbonyl]oxy]methyl ester, hydrochloride (1:1) Preparation Products And Raw materials
Raw materials
Preparation Products
3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 5-acetyl-4,5,6,7-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, [[(1-ethylpropoxy)carbonyl]oxy]methyl ester, hydrochloride (1:1) Suppliers
Global( 3)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
Suzhou Meishi Biotechnology Co., Ltd. | 1173954148q | meishipharma@126.com | China | 20035 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
Suzhou Meishi Biotechnology Co., Ltd. | 58 |
3H-Imidazo[4,5-c]pyridine-4-carboxylic acid, 5-acetyl-4,5,6,7-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, [[(1-ethylpropoxy)carbonyl]oxy]methyl ester, hydrochloride (1:1)
TA-606 free
190602-72-3
C33H40ClN7O6