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Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide

Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide structure

CAS No.: 70169-39-0

Chemical Name:: Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide

Synonyms: WAY-358024;2-hydroxy-N'-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)benzohydrazide;Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide

CBNumber:: CB110739003

Molecular Formula:: C15H11N3O3

Molecular Weight:: 281.27

MDL Number:

MOL File:: 70169-39-0.mol

Last updated:2025-04-18 09:51:37

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Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide Properties

Melting point	>250 °C
Density	1.44±0.1 g/cm3(Predicted)
pka	8.26±0.30(Predicted)

Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide Chemical Properties,Uses,Production

Uses

GSK-3β inhibitor 26 (Compound D14) is a GSK-3β inhibitor with an IC50 of 18.23 μM. GSK-3β inhibitor 26 can be used in the research of cancer, inflammation and neurodegenerative diseases[1].

IC 50

GSK-3β: 18.23 μM (IC₅₀)

References

[1] Dou X, et al. Discovery of new GSK-3β inhibitors through structure-based virtual screening. Bioorg Med Chem Lett. 2018 Jan 15;28(2):160-166. DOI:10.1016/j.bmcl.2017.11.036

Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4757	55
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	71826	60
Shanghai SuperLan Chemcial Technique Centre	0-2022843681 15618226720	chaolaichem@foxmail.com	China	12476	58
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	486064515@qq.com	China	4755	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	48457	58
Shaoguan Qicheng Biotechnology Co., Ltd	18122215013	780229652@qq.com	China	1292	58

Supplier	Advantage
Aladdin Scientific	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shanghai SuperLan Chemcial Technique Centre	58
Jinan Jiuli Biotechnology Co. , Ltd.	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
Shaoguan Qicheng Biotechnology Co., Ltd	58

Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide WAY-358024 2-hydroxy-N'-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)benzohydrazide 70169-39-0