ChemicalBook >> CAS DataBase List >>JB062
JB062
- CAS No.
- 2417988-00-0
- Chemical Name:
- JB062
- Synonyms
- JB062;JB062, 10 mM in DMSO;4-Hydroxy-3-(1-((4-methoxybenzyl)imino)ethyl)-2H-chromen-2-one
- CBNumber:
- CB112867315
- Molecular Formula:
- C19H17NO4
- Molecular Weight:
- 323.35
- MDL Number:
- MOL File:
- 2417988-00-0.mol
Last updated:2025-11-10 14:44:25
JB062 Chemical Properties,Uses,Production
Uses
JB062 is a nonmuscle myosin inhibitor with IC50 values of 1.6, 5.4, and >100 μM for Skeletal muscle myosin, Cardiac muscle myosin, and Smooth muscle myosin II, respectively. JB062 has cytotoxic to human cancer cells but not normal cells. JB062 can be used in research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy[1].
References
[1] Smith JD, et, al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2022 Dec 12;247:115008. DOI:10.1016/j.ejmech.2022.115008
JB062 Preparation Products And Raw materials
Raw materials
Preparation Products
JB062 Suppliers
Global( 14)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2391 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 8011 | 55 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59936 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24961 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| Changsha Fuzhen Biotechnology Co.,LTD | 0731-13823398 15111215862 | 313359644@qq.com | China | 4161 | 58 |
| Hubei wei shi reagent group ltd., company | 027-59101766 13125137661 | 2853877621@qq.com | China | 7979 | 58 |
JB062
4-Hydroxy-3-(1-((4-methoxybenzyl)imino)ethyl)-2H-chromen-2-one
JB062, 10 mM in DMSO
2417988-00-0





