cryogenine
- CAS No.
- 5286-10-2
- Chemical Name:
- cryogenine
- Synonyms
- Lythrine;20H-6,20-Methano-11,15-metheno-1H,8H-benzo[g]pyrido[2,1-d][1,5]oxaazacyclohexadecin-8-one, 2,3,4,4a,5,6-hexahydro-14-hydroxy-17,18-dimethoxy-, (4aS,6S,9Z,20S)-
- CBNumber:
- CB11345516
- Molecular Formula:
- C26H29NO5
- Molecular Weight:
- 435.51216
- MDL Number:
- MOL File:
- 5286-10-2.mol
| Melting point | 241-2°C |
|---|---|
| Boiling point | 655.4±55.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| solubility | DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml |
| form | A crystalline solid |
| pka | 8.27±0.20(Predicted) |
| FDA UNII | S16X2W9YAB |
cryogenine price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25804 | Lythrine ≥95% | 5286-10-2 | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 25804 | Lythrine ≥95% | 5286-10-2 | 5mg | $270 | 2024-03-01 | Buy |
| Cayman Chemical | 25804 | Lythrine ≥95% | 5286-10-2 | 10mg | $477 | 2024-03-01 | Buy |
| Cayman Chemical | 25804 | Lythrine ≥95% | 5286-10-2 | 25mg | $1041 | 2024-03-01 | Buy |
| AK Scientific | 8613CP | Lythrine | 5286-10-2 | 1mg | $166 | 2021-12-16 | Buy |
cryogenine Chemical Properties,Uses,Production
Description
This alkaloid is also present in Heimia salicifolia Link & Otto and is obtained as long, glistening needles from either CH2Clr light petroleum or CH2Cl2-MeOH. It is dextrorotatory with [α]25D + 40.6° (c 0.3, CHC13) and the ultraviolet spectrum shows two absorption maxima at 260 and 284 mJ.1. The following salts and derivatives have been prepared to characterize the base: the hydrochloride as prisms, m.p. 325-331 °c (dec.); the acetyl derivative, m.p. In-3°C; [o:lf,S + 33.1 ° (c 0.75, CHC13) and the methyl ether, m.p. 239-24loC; the latter yielding a crystalline hydrochloride and hydrobromide containing MeOH of crystalliza_x0002_tion.
Description
Lythrine is an alkaloid originally isolated from H. salicifolia that inhibits prostaglandin synthetase (IC50 = 469 μM).
Definition
ChEBI: (+)-Lythrine is a member of quinolizidines.
References
Blomster, Schwarting, Bobbitt., LZoydia, 27, 15 (1964) Douglas et aZ., ibid, 27, 25 (1964) Crystal structure: Zacharias et aZ., Experientia, 21, 247 (1965) Stereochemistry: Ferris, Boyce, Briner., J. Amer. Chern. Soc., 93,2942 (1971) Ferris etaZ., ibid, 93,2963 (1971)
cryogenine Preparation Products And Raw materials
Raw materials
Preparation Products
cryogenine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 58 |