(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester
- CAS No.
- 5980-01-8
- Chemical Name:
- (20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester
- Synonyms
- Lochneridine;(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester;Curan-17-oic acid, 2,16-didehydro-20-hydroxy-, methyl ester, (20α)- (9CI)
- CBNumber:
- CB12187337
- Molecular Formula:
- C20H24N2O3
- Molecular Weight:
- 340.42
- MDL Number:
- MOL File:
- 5980-01-8.mol
| Melting point | 211-4°C (dec.). |
|---|---|
| Boiling point | 507.7±50.0 °C(Predicted) |
| alpha | D26 +607.5° (chloroform) |
| Density | 1.34±0.1 g/cm3(Predicted) |
| pka | 5.5 in 66% DMF |
| FDA UNII | 30V9I8T4ZT |
(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester Chemical Properties,Uses,Production
Description
A further alkaloid from Vinca rosea L., forming colourless prisms when crystallized from MeOH. The ultraviolet spectrum has absorption maxima at 230, 293 and 328 mil. The base contains a tertiary hydroxyl group and an imino group and, with AC20 in pyridine, furnishes akuammicine (q.v.), by dehydration. Reduction with Zn dust in MeOH-H2S04 yields 2: 16-dihydroakuammicine after preparative thin-layer chromatography on silica gel.
References
Svoboda et al., J. Pharm. Sci., 50, 409 (1961)
Structure:
Nakagawa et at., Chem. Ind., 1986 (1962)
(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester Suppliers
Global( 1)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
(20S)-2,16-Didehydro-20-hydroxycuran-17-oic acid methyl ester
Lochneridine
Curan-17-oic acid, 2,16-didehydro-20-hydroxy-, methyl ester, (20α)- (9CI)
5980-01-8
C20H24O3N2