ChemicalBook >> CAS DataBase List >>Fmoc-norArg(pbf)-OH

Fmoc-norArg(pbf)-OH

Fmoc-norArg(pbf)-OH structure

CAS No.: 1313054-32-8

Chemical Name:: Fmoc-norArg(pbf)-OH

Synonyms: Fmoc-norArg(pbf)-OH;(S)-2-(Fmoc-amino)-4-[[amino(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)methylene]amino]butanoic Acid;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)butanoic acid;(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}butanoic acid;(S,E)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(N'-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)formohydrazonamido)butanoic acid;(2S)-4-[[amino-[(2,2,4,6,7-pentamethyl-3~{H}-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)butanoic acid;(2S)-4-[[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid;Butanoic acid, 4-[[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-

CBNumber:: CB12470877

Molecular Formula:: C33H38N4O7S

Molecular Weight:: 634.74

MDL Number:: MFCD15142017

MOL File:: 1313054-32-8.mol

Last updated:2024-01-26 15:56:30

Request For Quotation

Fmoc-norArg(pbf)-OH Properties

Density	1.38±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	3.75±0.10(Predicted)
InChIKey	FWOIXFWITXCUKI-NDEPHWFRSA-N
SMILES	C(O)(=O)[C@@H](NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)CCNC=NNS(C1=C(C)C(C)=C2OC(C)(C)CC2=C1C)(=O)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

Fmoc-norArg(pbf)-OH price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AK Scientific	8413EA	Fmoc-norArg(Pbf)-OH	1313054-32-8	100mg	$162	2021-12-16	Buy
ChemPep	180195	Fmoc-norArg(Pbf)-OH	1313054-32-8	1g	$400	2021-12-16	Buy
Iris Biotech GmbH	FAA8280	Fmoc-L-Agb(Pbf)-OH	1313054-32-8	1g	$607.5	2021-12-16	Buy
Activate Scientific	AS117539	Fmoc-norArg(Pbf)-OH 97+%	1313054-32-8	5G	$1134	2021-12-16	Buy
ChemPep	180195	Fmoc-norArg(Pbf)-OH	1313054-32-8	5g	$1200	2021-12-16	Buy

Product number	Packaging	Price	Buy
8413EA	100mg	$162	Buy
180195	1g	$400	Buy
FAA8280	1g	$607.5	Buy
AS117539	5G	$1134	Buy
180195	5g	$1200	Buy

Fmoc-norArg(pbf)-OH Chemical Properties,Uses,Production

Chemical Properties

The IUPAC Name of Fmoc-norArg(pbf)-OH is rac-(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)propanoic acid. Pbf is 2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl.
In addition, conjugation of Arg-containing peptides is difficult due to the steric hindrance of Pbf in a side chain as a protecting group, resulting in low peptide yield or even synthesis failure[1].

References

[1] Keiichi Yamada . “Efficient solid-phase synthesis of cyclic RGD peptides under controlled microwave heating.” Tetrahedron Letters 53 9 (2012): Pages 1066-1070.

Fmoc-norArg(pbf)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

Fmoc-norArg(pbf)-OH Suppliers

Global( 29)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alpha Biopharmaceuticals Co., Ltd	+86-411-39042497 +8613921981412	sales@alphabiopharm.com	China	886	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006608290; 18621169109	market03@meryer.com	China	40241	62
Alabiochem Tech.Co., Ltd.	0512-58900862 400-0707518	sales@alabiochem.com	China	995	59
Shanghai Jian Chao Chemical Technology Co., Ltd.	021-50430803 18017383231	983544897@qq.com	China	9352	55
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	41438	60
Shanghai GL Peptide Ltd.	+86-21-61263310; 13764994101 13764994101	fisherwang@glschina.com	China	8457	55
Alabiotech Inc.	001-619-354-5251	sales@alabiotech-e.com	United States	972	60
Amatek Scientific Co. Ltd.	0512-56316828	info@amateksci.com	China	28822	58

Supplier	Advantage
Alpha Biopharmaceuticals Co., Ltd	58
Nextpeptide Inc	58
LEAPCHEM CO., LTD.	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alabiochem Tech.Co., Ltd.	59
Shanghai Jian Chao Chemical Technology Co., Ltd.	55
Bide Pharmatech Ltd.	60
Shanghai GL Peptide Ltd.	55
Alabiotech Inc.	60
Amatek Scientific Co. Ltd.	58

Fmoc-norArg(pbf)-OH (2S)-4-[[amino-[(2,2,4,6,7-pentamethyl-3~{H}-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)butanoic acid (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}butanoic acid Butanoic acid, 4-[[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)- (2S)-4-[[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid (S,E)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(N'-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)formohydrazonamido)butanoic acid (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)butanoic acid (S)-2-(Fmoc-amino)-4-[[amino(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)methylene]amino]butanoic Acid 1313054-32-8 C33H38N4O7S amino acid amino acids