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A-796260

A-796260 Structure
A-796260 structure
CAS No.
895155-26-7
Chemical Name:
A-796260
Synonyms
A-796260;(1-(2-Morpholinoethyl)-1H-indol-3-yl)(2,2,3,3-tetraMethylcyclopropyl)Methanone;[1-(2-morpholin-4-ylethyl)indol-3-yl]-(2,2,3,3-tetramethylcyclopropyl)methanone;[1-[2-(4-Morpholinyl)ethyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone;[1-(2-Morpholin-4-ylethyl)-1H-indol-3-yl]-(2,2,3,3-tetraMethylcyclopropyl)Methanone;Methanone, [1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-
CBNumber:
CB12563324
Molecular Formula:
C22H30N2O2
Molecular Weight:
354.49
MDL Number:
MOL File:
895155-26-7.mol
Last updated:2023-06-08 09:02:00

A-796260 Properties

Boiling point 492.7±35.0 °C(Predicted)
Density 1.16
solubility DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 5 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.16 mg/ml; Methanol: 1 mg/ml
form A crystalline solid
pka 7.07±0.10(Predicted)
FDA UNII 5N69DXA53Z

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

A-796260 Chemical Properties,Uses,Production

Description

A-796260 is a synthetic cannabinoid (CB) that shows high selectivity for the CB2 receptor (Ki = 0.77 nM) over the CB1 receptor (Ki = 2,100 nM). It also shows efficacy in vivo in models of inflammatory, post-operative, neuropathic, and osteoarthritic pain, activities which are selectively blocked by CB2 receptor-selective antagonists. This product is intended for research and forensic uses.

Uses

A-796,260 is a synthetic cannabinoid that shows high selectivity towards CB2 receptor over the CB1 receptor. A-796,260 showed high efficacy in models of inflammatory, post-operative, neuropathic and OA pain in vivo.

A-796260 Preparation Products And Raw materials

Raw materials

Preparation Products

A-796260 [1-(2-Morpholin-4-ylethyl)-1H-indol-3-yl]-(2,2,3,3-tetraMethylcyclopropyl)Methanone [1-[2-(4-Morpholinyl)ethyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone (1-(2-Morpholinoethyl)-1H-indol-3-yl)(2,2,3,3-tetraMethylcyclopropyl)Methanone [1-(2-morpholin-4-ylethyl)indol-3-yl]-(2,2,3,3-tetramethylcyclopropyl)methanone Methanone, [1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)- 895155-26-7 Aromatics Indole Derivatives Intermediates & Fine Chemicals Neurochemicals Pharmaceuticals Research Chemical