ChemicalBook >> CAS DataBase List >>(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

CAS No.
475473-26-8
Chemical Name:
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
Synonyms
CORM-3;Carbon monoxide releasing molecule 3;Tricarbonylchloro(glycinato)ruthenium;Tricarbonylchloro(glycinato)ruthenium (II);(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium;(OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium;Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-;inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR)
CBNumber:
CB12717709
Molecular Formula:
C5H3ClNO5Ru
Molecular Weight:
293.6
MDL Number:
MFCD07364048
MOL File:
475473-26-8.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Properties

storage temp. -20°C
solubility H2O: soluble20mg/mL, clear
form powder
color light yellow to dark yellow
Water Solubility Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

WGK Germany  3

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0496 CORM-3 475473-26-8 10mg $123 2024-03-01 Buy
Sigma-Aldrich SML0496 CORM-3 475473-26-8 50mg $496 2024-03-01 Buy
Tocris 5320 CORM3 475473-26-8 50 $357 2021-12-16 Buy
Usbiological 255030 CORM 3 475473-26-8 10mg $333 2021-12-16 Buy
TRC C724813 CORM3 475473-26-8 25mg $695 2021-12-16 Buy
Product number Packaging Price Buy
SML0496 10mg $123 Buy
SML0496 50mg $496 Buy
5320 50 $357 Buy
255030 10mg $333 Buy
C724813 25mg $695 Buy

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Chemical Properties,Uses,Production

Uses

CORM-3 (carbon monoxide (CO) releasing molecule-3) has been used to study its effect on NLRP3 (leucine-rich-repeat-containing receptor, pyrin-domain-containing 3) inflammasome activation via glycolysis in macrophages and also on hyperglycemia-induced IL-1β (interleukin-1 β) production. It has also been used to study its protective function against H2O2-induced apoptosis using primary rabbit lens epithelial cells.

Biochem/physiol Actions

CORM-3 is a water-soluble carbon monoxide (CO) releasing molecule that can be used to study the effects of CO on cellular systems. Carbon monoxide (CO), produced during the degradation of heme by the enzyme heme oxygenase, has recently been found to be an important gaseous signaling mediator in mammalian cells CORM-3 has been shown to have anti-inflammatory and cardioprotective activity.

storage

Store at -20°C

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Preparation Products And Raw materials

Raw materials

Preparation Products

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Suppliers

Global( 64)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
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Zhengzhou Alfa Chemical Co.,Ltd
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Career Henan Chemica Co
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InvivoChem
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Nantong HI-FUTURE Biology Co., Ltd.
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TargetMol Chemicals Inc.
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Aladdin Scientific
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Energy Chemical 021-021-58432009 400-005-6266 sales8178@energy-chemical.com China 44751 61
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2784 58

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Spectrum

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium CORM-3 Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)- Carbon monoxide releasing molecule 3 Tricarbonylchloro(glycinato)ruthenium (II) Tricarbonylchloro(glycinato)ruthenium inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR) (OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium 475473-26-8 C5H4ClNO5Ru Inhibitors