Anti-hPc2 antibody produced in rabbit
- CAS No.
- Chemical Name:
- Anti-hPc2 antibody produced in rabbit
- Synonyms
- Anti-Pc2 antibody produced in rabbit;Anti-hPc2 antibody produced in rabbit;Anti-CBX4 antibody produced in rabbit;Anti-Polycomb 2 homolog antibody produced in rabbit;Anti-Chromobox homolog 4 (Pc class homolog, Drosophila);Anti-E3 SUMO-protein ligase CBX4 antibody produced in rabbit;Anti-Chromobox protein homolog 4 antibody produced in rabbit
- CBNumber:
- CB12888928
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-hPc2 antibody produced in rabbit price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | HPA012021 | Anti-CBX4 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | 100μL | $555 | 2025-07-31 | Buy | |
Sigma-Aldrich | HPA008228 | Anti-CBX4 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100 μL | $555 | 2025-07-31 | Buy | |
Sigma-Aldrich | AV30002 | Anti-CBX4 antibody produced in rabbit affinity isolated antibody | 100μL | $541 | 2025-07-31 | Buy | |
Sigma-Aldrich | HPA012021 | Anti-CBX4 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | 25μL | $282 | 2023-06-20 | Buy | |
Sigma-Aldrich | AV30002 | Anti-CBX4 antibody produced in rabbit affinity isolated antibody | 100ul | $390 | 2021-12-16 | Buy |
Anti-hPc2 antibody produced in rabbit Chemical Properties,Uses,Production
Uses
Anti-CBX4 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 4-8 μg/ml is suitable.
Biological Activity
Chromobox homolog 4 (CBX4) is mainly responsible for formation of large multimeric complexes called polycomb group (PcG) bodies which take part in the repression of gene expression. It is involved in the recruitment of the transcriptional corepressor C-terminal binding protein (CtBP) to PcG bodies and promotes its sumoylation. This facilitates the transfer of SUMO (Small ubiquitin-related modifier) to CtBP. CBX4 also covalently modifies Smad-1 interacting protein 1 (SIP1) by sumoylation and hence acts as a SUMO E3 ligase. E-cadherin repression by SIP1 is partially inhibited due to the sumoylation.
Anti-hPc2 antibody produced in rabbit Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-hPc2 antibody produced in rabbit Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
Supplier | Advantage |
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Merck KGaA | 58 |