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Adenine

Adenine
Adenine structure
CAS No.
73-24-5
Chemical Name:
Adenine
Synonyms
ANE;Ade;Adenin;Leuco-4;ADENINE;usafcb-18;Crytidine;adensoine;USAF CB-18;ADENINE(P)
CBNumber:
CB1323708
Molecular Formula:
C5H5N5
Formula Weight:
135.13
MOL File:
73-24-5.mol

Adenine Properties

Melting point:
>360 °C(lit.)
Boiling point:
238.81°C (rough estimate)
Density 
1.3795 (rough estimate)
refractive index 
1.7000 (estimate)
Flash point:
220°C
storage temp. 
Store at RT.
solubility 
0.5 M HCl: soluble20mg/mL, Grade III, colorless to faint yellow or tan
pka
4.12(at 25℃)
form 
Liquid or Solid
color 
Clear colorless to light yellow
Odor
Odorless
PH Range
7
Water Solubility 
0.5 g/L (20 ºC)
Sublimation 
220 ºC
Merck 
14,152
BRN 
5777
Stability:
Stable. Moisture-sensitive. Incompatible with strong oxidizing agents.
InChIKey
GFFGJBXGBJISGV-UHFFFAOYSA-N
CAS DataBase Reference
73-24-5(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
JAC85A2161
NCI Dictionary of Cancer Terms
ADE; adenine
NIST Chemistry Reference
Adenine(73-24-5)
EPA Substance Registry System
Adenine (73-24-5)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS06,GHS07
Signal word  Danger
Hazard statements  H315-H319-H301
Precautionary statements  P301+P310a-P321-P501a-P264-P270-P280-P301+P310+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P405-P501-P301+P310
Hazard Codes  Xn,Xi
Risk Statements  22-20/21/22
Safety Statements  26-36
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  AU6125000
8-10-23
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29335990
Toxicity LD50 orally in rats: 745 mg/kg (Philips)
NFPA 704
1
2 0

Adenine price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1152-M Adenine 73-24-5 10gm $69.3 2020-08-18 Buy
Sigma-Aldrich 1012101 Adenine United States Pharmacopeia (USP) Reference Standard 73-24-5 200mg $325 2020-08-18 Buy
TCI Chemical A0149 Adenine >99.0%(HPLC)(T) 73-24-5 25g $56 2020-06-24 Buy
TCI Chemical A0149 Adenine >99.0%(HPLC)(T) 73-24-5 250g $336 2020-06-24 Buy
Alfa Aesar A14906 Adenine, 99% 73-24-5 50g $117 2020-06-24 Buy

Adenine Chemical Properties,Uses,Production

Description

adenine is one of the purine nitrogenous bases that composes DNA and RNA; composed of two carbon–nitrogen rings. Adenine bonds with thymine in DNA and with uracil in RNA (see base pairing rule); it is also a major component of other molecules such as adenosine triphosphate.

Chemical Properties

White to almost white crystalline powder

Chemical Properties

Adenine is a prominent member of the family of naturally occurring purines. Adenine occurs not only in ribonucleic acids (RNA), and deoxyribonucleic acids (DNA), but in nucleosides, such as adenosine, and nucleotides, such as adenylic acid, which may be linked with enzymatic functions quite apart from nucleic acids. Adenine, in the form of its ribonucleotide, is produced in mammals and fowls endogenously from smaller molecules and no nutritional essentiality is ascribed to it. In the nucleosides, nucleotides, and nucleic acids, the attachment or the sugar moiety is at position 9.
The purines and pyrimidines absorb ultraviolet light readily, with absorption peaks at characteristic frequencies. This has aided in their identification and quantitative determination.

Physical properties

Adenine is a white crystalline substance that is an important biological compound found in deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and adenosine triphosphate (ATP). It was once commonly referred to as vitamin B4 but is no longer considered a vitamin. Adenine is derived from purine. Purine is a heterocyclic compound.

History

Adenine is one of the two purines found in DNA and RNA. The other is guanine. Adenine and guanine are called bases in reference to DNA and RNA. A nucleic acid base attached to ribose forms a ribonucleoside. Adenine combined with ribose produces the nucleoside adenosine.

Uses

local antiseptic

Uses

Vitamin B4

Uses

Widespread throughout animal and plant tissues combined with niacinamide, d-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coa laninedehydrase. It is used in microbial determination of niacin; in research on heredity, virus diseases, and cancer.

Uses

enteric coating

Uses

A purine nucleobase and a component of DNA

Definition

A nitrogenous base found in DNA and RNA. It is also a constituent of certain coenzymes and when combined with the sugar ribose it forms the nucleoside adenosine found in AMP, ADP, and ATP. Adenine has a purine ring structure.

Definition

adenine: A purine derivative. It isone of the major component bases ofnucleotides and the nucleic acidsDNA and RNA.

Definition

ChEBI: The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6.

Synthesis Reference(s)

Journal of the American Chemical Society, 88, p. 3829, 1966 DOI: 10.1021/ja00968a028

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

Purification Methods

Crystallise adenine from distilled water. [Beilstein 26 III/IV 3561.]

Adenine Preparation Products And Raw materials

Raw materials

Preparation Products


Adenine Suppliers

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Related articles


View Lastest Price from Adenine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-07-03 Adenine
73-24-5
US $1.00 / KG 1KG 99% 100T Henan Xiangtong Chemical Co., Ltd.
2020-07-13 Adenine
73-24-5
US $2.00 / KG 1KG 99.7% 500 Ton/Tons per Month Hebei Xibaijie Biotechnology Co., Ltd.
2020-04-22 Adenine
73-24-5
US $0.00 / mg 20mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.

Adenine Spectrum


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