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(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

CAS No.
2093243-16-2
Chemical Name:
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Synonyms
Nintedanib-013-Z;Nidanibu Impurity 8;Nidanib Impurity 50;Nintedanib impurities11;(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;Nintedanib impurity 12/Methyl (Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(hydroxyphenylmethylene)-2-oxo-, methyl ester, (3Z)-
CBNumber:
CB14656048
Molecular Formula:
C17H13NO4
Molecular Weight:
295.29
MDL Number:
MOL File:
2093243-16-2.mol
MSDS File:
SDS
Last updated:2026-03-18 11:52:23
Product description Number Pack Size Price
(Z)-Methyl3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate M323629 50mg $235

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Properties

Melting point >215°C (dec.)
Boiling point 536.9±50.0 °C(Predicted)
Density 1.357±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka 4.50±1.00(Predicted)
color Yellow to Dark Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M323629 (Z)-Methyl3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 2093243-16-2 50mg $235 2021-12-16 Buy
Product number Packaging Price Buy
M323629 50mg $235 Buy

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties,Uses,Production

Uses

(Z)-Methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is a useful intermediate for the preparation of nintedanib esylate. Nintedanib is a drug for the treatment of idiopathic pulmonary fibrosis.

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Suppliers

Global( 50)Suppliers
Supplier Tel Email Country ProdList Advantage
Moxin Chemicals
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S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5157 50
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18422 56
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View Lastest Price from (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Nintedanib Impurity 50 pictures 2025-12-16 Nintedanib Impurity 50
2093243-16-2
US $0.00-0.00 / mg 10mg 95%+ 100000000 Moxin Chemicals
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Nintedanib impurity 12/Methyl (Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Nintedanib-013-Z Nidanibu Impurity 8 Nintedanib impurities11 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(hydroxyphenylmethylene)-2-oxo-, methyl ester, (3Z)- Nidanib Impurity 50 2093243-16-2