Anti-EpCAM antibody, Mouse monoclonal

CAS No.
Chemical Name:
Anti-EpCAM antibody, Mouse monoclonal
Synonyms
Anti-EpCAM antibody, Mouse monoclonal
CBNumber:
CB14669198
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Anti-EpCAM antibody, Mouse monoclonal Properties

storage temp. -20°C
form buffered aqueous solution

Anti-EpCAM antibody, Mouse monoclonal price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB4200690 Anti-EpCAM antibody, Mouse monoclonal clone Ber-EP4, hybridoma cell culture supernatant 100μL $463 2023-06-20 Buy
Product number Packaging Price Buy
SAB4200690 100μL $463 Buy

Anti-EpCAM antibody, Mouse monoclonal Chemical Properties,Uses,Production

Uses

Anti-EpCAM antibody has been used in:

  • immunofluorescence
  • immunohistochemistry
  • immunoprecipitation

General Description

Anti-EpCAM antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the hybridoma Ber-EP4 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human breast carcinoma cell line MCF-7. EpCAM (Epithelial cell adhesion molecule) is a highly conserved type I transmembrane glycoprotein. EpCAM is present on most epithelia tissues of the adult body and in undifferentiated rather than differentiated embryonic stem cells.

Biochem/physiol Actions

The epithelial cell adhesion molecule (EpCAM) is highly expressed in carcinomas. It regulates cell signalling, proliferation, migration and adhesion. Proteolytic cleavage of EpICD domain is crucial for tumor progression. EpCAM is highly expressed in breast cancer and is considered as a potential target for gene therapy. Deletions in the 3′ region of the EpCAM gene is associated with colorectal cancer based lynch syndrome. Single nucleotide polymorphism in EpCAM gene is associated with infant diarrheal disorder, congenital tufting enteropathy(CTE).

Anti-EpCAM antibody, Mouse monoclonal Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-EpCAM antibody, Mouse monoclonal Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-EpCAM antibody, Mouse monoclonal