ChemicalBook >> CAS DataBase List >>Amino-PEG5-t-butyl acetate
Amino-PEG5-t-butyl acetate
- CAS No.
- 2231845-67-1
- Chemical Name:
- Amino-PEG5-t-butyl acetate
- Synonyms
- NH2-PEG5-C1-Boc;H2N-PEG5-CH2COOtBu;NH2-PEG5-CH2COOtBu;Amino-PEG5-CH2COOtBu;Amino-PEG5-t-butyl acetate;tert-butyl 17-amino-3,6,9,12,15-pentaoxaheptadecanoate;3,6,9,12,15-Pentaoxaheptadecanoic acid,17-amino-, 1,1-dimethylethyl ester;H2N-PEG5-CH2COOtBu/3,6,9,12,15-Pentaoxaheptadecanoic acid, 17-amino-, 1,1-dimethylethyl ester
- CBNumber:
- CB14858565
- Molecular Formula:
- C16H33NO7
- Molecular Weight:
- 351.44
- MDL Number:
- MFCD31747106
- MOL File:
- 2231845-67-1.mol
Last updated:2023-02-23 14:24:01
Amino-PEG5-t-butyl acetate Chemical Properties,Uses,Production
Biological Activity
NH2-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Amino-PEG5-t-butyl acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Amino-PEG5-t-butyl acetate Suppliers
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Amino-PEG5-t-butyl acetate
3,6,9,12,15-Pentaoxaheptadecanoic acid,17-amino-, 1,1-dimethylethyl ester
H2N-PEG5-CH2COOtBu
NH2-PEG5-C1-Boc
NH2-PEG5-CH2COOtBu
tert-butyl 17-amino-3,6,9,12,15-pentaoxaheptadecanoate
H2N-PEG5-CH2COOtBu/3,6,9,12,15-Pentaoxaheptadecanoic acid, 17-amino-, 1,1-dimethylethyl ester
Amino-PEG5-CH2COOtBu
2231845-67-1