A-CRYSTALLIN
- CAS No.
- 11046-99-4
- Chemical Name:
- A-CRYSTALLIN
- Synonyms
- crystallin;CRYSTALLINS;A-CRYSTALLIN;α-Crystallin;bl-crystallin;bh-crystallin;βL-Crystallin;B S-CRYSTALLIN;hm-A-crystallin;α-crystallin from bovine eye lens
- CBNumber:
- CB1497968
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00070939
- MOL File:
- Mol file
| storage temp. | -20°C |
|---|---|
| form | lyophilized powder |
| EWG's Food Scores | 1 |
A-CRYSTALLIN price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C4163 | α-Crystallin from bovine eye lens lyophilized powder | 11046-99-4 | 5mg | $260 | 2024-03-01 | Buy |
| Sigma-Aldrich | C4163 | α-Crystallin from bovine eye lens lyophilized powder | 11046-99-4 | 25mg | $894 | 2024-03-01 | Buy |
| Sigma-Aldrich | C5163 | βL-Crystallin from bovine eye lens | 11046-99-4 | 25mg | $786 | 2023-01-07 | Buy |
A-CRYSTALLIN Chemical Properties,Uses,Production
Uses
α-Crystallin is a lens protein that contains two homologous subunits: αA- and αB-crystallins. α-Crystallin displays chaperone-like activity and plays an important role in maintaining lens transparency. It has been noted that in diabetic conditions of rats there is a decline in the chaperone activity of α-Crystallin. Research has shown that a dietary antioxidant, curcumin, can prevent this loss of chaperone activity.
General Description
β-Crystallin is the most heterogeneous of the crystallin classes, with at least six different gene products, at least ten different post-translational modifications, and quaternary structure variants from dimers to octamers. However, all sequences are highly conserved through evolution.
Biochem/physiol Actions
α-Crystallin is a small heat-shock protein that has chaperone-like activity, preventing protein aggregation in vitro. Point mutations in α-crystallin genes are believed to be responsible for hereditary cataract development.
A-CRYSTALLIN Preparation Products And Raw materials
Raw materials
Preparation Products
A-CRYSTALLIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Shanghai Yingxin laboratory equipment Co., Ltd | 021-021-59178156 15300768757 | 359382369@qq.com | China | 10367 | 58 |
| Shanghai Guchen Biotechnology Co., LTD | 021-34675735 19147740836 | 1986399151@qq.com | China | 9849 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Energy Chemical | 58 |
| Shanghai Yingxin laboratory equipment Co., Ltd | 58 |
| Shanghai Guchen Biotechnology Co., LTD | 58 |