ANTI-BCRP
- CAS No.
- Chemical Name:
- ANTI-BCRP
- Synonyms
- ANTI-MXR;ANTI-BCRP;Anti-ABCP;ANTI-ABCG2;Anti-CD338;ANTI-CDW338;Anti-EST157481;ANTI-HUMAN BCRP;ANTI-MXR (HUMAN);ANTI-BCRP (HUMAN)
- CBNumber:
- CB1756436
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03791618
- MOL File:
- Mol file
ANTI-BCRP price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SAB5700094 | Anti-ABCG2 antibody produced in rabbit | 100μL | $405 | 2024-03-01 | Buy | |
Sigma-Aldrich | B7185 | Anti-Breast Cancer Resistance Protein antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 200μL | $573 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB4300689 | Anti-ABCG2 antibody produced in rabbit affinity isolated antibody | 100μG | $490 | 2023-01-07 | Buy | |
Sigma-Aldrich | B7684 | Monoclonal Anti-Breast Cancer Resistance Protein antibody produced in mouse 250?μg/mL, clone BXP-34, tissue culture supernatant, aqueous solution | 1ML | $966 | 2023-01-07 | Buy | |
Sigma-Aldrich | B7059 | Monoclonal Anti-Breast Cancer Resistance Protein antibody produced in mouse ~250?μg/mL, clone BXP-21, tissue culture supernatant, aqueous solution | 1ML | $1030 | 2023-01-07 | Buy |
ANTI-BCRP Chemical Properties,Uses,Production
Uses
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
General Description
Anti-Breast Cancer Resistance Protein is developed in rabbit using as immunogen a synthetic peptide of human breast cancer resistance protein (BCRP). BCRP, also designated ABCG2, ABCP, placenta specific ATP-binding transporter and mitoxantrone-resistance protein (MXR), is a member of the ABCG subfamily of the large ATP binding cassette (ABC) transporter family of transmembrane proteins. BCRP is a half-transporter, with a single ATP binding cassette and transmembrane region. BCRP is normally expressed in human placental syncytiotrophoblasts, mammary ducts and lobules, endothelial cells and stem cells of different tissues.
Biochem/physiol Actions
Up regulation of breast cancer resistance protein (BCRP) expression may be found in vivo and in vitro in both drugs treated and untreated tumors of different types. Breast cancer resistance protein transports various xenobiotics to the extracellular space through a process energized by ATP hydrolysis. In addition, to its role in protecting cells and tissues against xenobiotics especially in the intestine, liver, placenta and the blood-brain barrier, BCRP appears to be involved in hypoxic defense mechanisms and the protection and regulation of stem cells.
ANTI-BCRP Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-BCRP Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |