ChemicalBook >> CAS DataBase List >>1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)-
1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)-
![1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)- Structure](CAS/20211123/GIF/884033-66-3.gif)
- CAS No.
- 884033-66-3
- Chemical Name:
- 1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)-
- Synonyms
- AG-17724 >=98% (HPLC);(R)-2-(2-naphthamido)-3-(5-fluoro-1H-benzo[d]imidazol-2-yl)propanoic acid;(R)-2-(2-Naphthamido)-3-(6-fluoro-1H-benzo[d]imidazol-2-yl)propanoic acid;1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)-
- CBNumber:
- CB18206865
- Molecular Formula:
- C21H16FN3O3
- Molecular Weight:
- 377.38
- MDL Number:
- MFCD28411616
- MOL File:
- 884033-66-3.mol
Last updated:2025-08-21 22:16:43
| Product description | Number | Pack Size | Price |
| AG-17724 ≥98% (HPLC) | PZ0268 | 5 mg | $103 |
| AG-17724 ≥98% (HPLC) | PZ0268 | 25 mg | $404 |
| Boiling point | 772.5±60.0 °C(Predicted) |
|---|---|
| Density | 1.437±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: 20mg/mL, clear (warmed) |
| form | powder |
| pka | 3.12±0.30(Predicted) |
| color | white to light brown |
| InChI | InChI=1/C21H16FN3O3/c22-15-7-8-16-17(10-15)24-19(23-16)11-18(21(27)28)25-20(26)14-6-5-12-3-1-2-4-13(12)9-14/h1-10,18H,11H2,(H,23,24)(H,25,26)(H,27,28)/t18-/s3 |
| InChIKey | NKMPZFCFXCJBEY-ZAWDOUAYNA-N |
| SMILES | C(C1=NC2=CC(F)=CC=C2N1)[C@H](C(=O)O)NC(C1C=CC2C=CC=CC=2C=1)=O |&1:11,r| |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)- price
1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)- Chemical Properties,Uses,Production
Uses
PIN1 inhibitor 5 (compound 7) is a PIN1 inhibitor (Ki=0.08 μM) ,which can be used in cancer research[1].
Biological Activity
AG-17724 is a potent peptidyl-prolyl isomerase (PPIase) Pin1 inhibitor.
References
[1] Chuangxing Guo, et al. Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4187-91. DOI:10.1016/j.bmcl.2014.07.044
1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)- Suppliers
Global( 13)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19962 | 58 |
| Nantong Weinedi Pharmaceutical Technology Co., Ltd | 18071612016 | 706531907@qq.com | China | 933 | 58 |
| Chunchuang (Wuhan) Technology Co., Ltd | 15727060112 | yutianchun2007@126.com | China | 9803 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Wuhan Topule | +86-02787215551 +86-19945035818 | 2936752263@qq.com | China | 7987 | 58 |
| Wuhan Augda Biotechnology Co., Ltd | 15071299552 | 262933239@qq.com | China | 7055 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1248 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24961 | 58 |
| Xianning Shen Lan Biomedical Research and Development Co., Ltd. | 18171815831 | 1341138380@qq.com | China | 4313 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5929 | 58 |
View Lastest Price from 1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)- manufacturers
1H-Benzimidazole-2-propanoic acid, 6-fluoro-α-[(2-naphthalenylcarbonyl)amino]-, (αR)-
AG-17724 >=98% (HPLC)
(R)-2-(2-Naphthamido)-3-(6-fluoro-1H-benzo[d]imidazol-2-yl)propanoic acid
(R)-2-(2-naphthamido)-3-(5-fluoro-1H-benzo[d]imidazol-2-yl)propanoic acid
884033-66-3
