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ChemicalBook >> CAS DataBase List >>2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Structure
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- structure
CAS No.
2408882-54-0
Chemical Name:
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-
Synonyms
BCL6-IN-6;BCL6 IN 6,BCL6IN6;2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-
CBNumber:
CB211207269
Molecular Formula:
C27H31FN6O2S
Molecular Weight:
522.64
MDL Number:
MOL File:
2408882-54-0.mol
Last updated:2025-12-03 18:03:33
Request For Quotation

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Properties

Density 1.301±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 11.58±0.70(Predicted)
color Light yellow to yellow

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Chemical Properties,Uses,Production

Uses

BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL)[1].

Biological Activity

BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL)[1].

References

[1]. Guo W, et al. Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth. J Med Chem. 2020;63(2):676-695.

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2391 55
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 9125 58
Absin Bioscience Inc. 021-38015121 18438616290 lanwu@univ-bio.com China 24731 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59936 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Hubei wei shi reagent group ltd., company 027-59101766 13125137661 2853877621@qq.com China 7979 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29257 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 Sales@sangon.com China 6710 58
Henan Jinbak New Material Technology Co., Ltd 18737135779 1169001743@qq.com China 95 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Beckham Medical Technology Co., Ltd 55
Shanghai Chaolan Chemical Technology Center 58
Absin Bioscience Inc. 58
Bide Pharmatech Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Hubei wei shi reagent group ltd., company 58
TargetMol Chemicals Inc. 58
Sangon Biotech (Shanghai) Co.,Ltd. 58
Henan Jinbak New Material Technology Co., Ltd 58

View Lastest Price from 2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BCL6-IN-6 pictures 2025-12-05 BCL6-IN-6
2408882-54-0
 US $41.00-179.00 / mg 98.90% 10g TargetMol Chemicals Inc.
  • BCL6-IN-6 pictures
  • BCL6-IN-6
    2408882-54-0
  • US $41.00-179.00 / mg
  • 98.90%
  • TargetMol Chemicals Inc.

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Spectrum

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-(2408882-54-0)1HNMR
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- BCL6-IN-6 BCL6 IN 6,BCL6IN6 2408882-54-0 C27H31FN6O2S