Isoetharine Hydrochloride
- CAS No.
- 50-96-4
- Chemical Name:
- Isoetharine Hydrochloride
- Synonyms
- Dilabron hydrochloride;Isoetarin hydrochloride;Isoetarine hydrochloride;Isoctarine hydrochloride;Bronkometer hydrochloride;Isoetharine hydrochloride;Etyprenaline hydrochloride;MUFDLGGSOCHQOC-UHFFFAOYSA-N;(R,*)-()-4-[1-hydroxy-2-[(1-methylethyl)amino]butyl]pyrocate...;1-(3,4-Dihydroxyphenyl)-2-isopropylamino-1-butanol hydrochloride
- CBNumber:
- CB21261224
- Molecular Formula:
- C13H22ClNO3
- Molecular Weight:
- 275.77
- MDL Number:
- MFCD01732794
- MOL File:
- 50-96-4.mol
| CAS DataBase Reference | 50-96-4 |
|---|---|
| EWG's Food Scores | 1 |
| FDA UNII | 51V8U784H3 |
Isoetharine Hydrochloride Chemical Properties,Uses,Production
Uses
Isoetharine Hydrochloride is hydrochloride salt of isoetharine which is β2-adrenergic receptor agonist. It can be used to give quick relief for bronchospasm and asthma. However, It may be potent in producing resistantce to β-adrenoceptor stimulants.
brand name
Beta-2 (Nephron);Bronkosol (Sanofi Aventis).
Clinical Use
The α-ethyl group confers β2-selectivity, and the β-hydroxyl group and catechol nucleus makes this a direct-acting drug. It is susceptible to COMT metabolism; however, the α-ethyl group inhibits MAO. Therefore, one would expect some oral activity.
Side effects
Isoetharine is dispensed as a solution only for inhalation administration to treat reversible bronchospasm of asthma. It has fallen into relative disuse, because with high doses, there is a significant incidence of cardiovascular (β1-receptor) adverse effects and it has a low β2-receptor potency compared to newer β2-selective agonists. It has a 2- to 4-minute onset of action when inhaled and a duration of action of 3 hours. Isoetharine has adverse effects similar to those of EPI, including palpitations, tachycardia, nausea and vomiting, dizziness, tremor, and headache. Isoetharine may cause decreased levels of theophylline when coadministered. Cardiovascular effects are a concern when isoetharine is taken with other asthma drugs.
Isoetharine Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973186 4009686088 | 3193328036@qq.com | China | 18352 | 68 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |