ISIS 329993
- CAS No.
- 827355-42-0
- Chemical Name:
- ISIS 329993
- Synonyms
- ISIS 329993;ISIS329993(Synonyms:ISIS-CRPRx)
- CBNumber:
- CB214271995
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
ISIS 329993 Chemical Properties,Uses,Production
Uses
ISIS 329993 (ISIS-CRPRx) is an antisense oligonucleotide targeting to C-reactive protein (CRP). ISIS-CRPRx has been tested in a rodent model of rheumatoid arthritis (RA) and was shown to improve the clinical signs of arthritis
References
[1] Warren MS, Hughes SG, Singleton W, Yamashita M, Genovese MC. Results of a proof of concept, double-blind, randomized trial of a second generation antisense oligonucleotide targeting high-sensitivity C-reactive protein (hs-CRP) in rheumatoid arthritis.?Arthritis Res Ther. 2015;17(1):80. DOI:10.1186/s13075-015-0578-5
[2] Noveck R, Stroes ES, Flaim JD, et al. Effects of an antisense oligonucleotide inhibitor of C-reactive protein synthesis on the endotoxin challenge response in healthy human male volunteers.?J Am Heart Assoc. 2014;3(4):e001084. DOI:10.1161/JAHA.114.001084
ISIS 329993 Preparation Products And Raw materials
Raw materials
Preparation Products
ISIS 329993 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai meikai technology co., ltd | 021-68689288 15300790979 | info@mkbio.com.cn | China | 5000 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai meikai technology co., ltd | 58 |
