NPPDGF
- CAS No.
- Chemical Name:
- NPPDGF
- Synonyms
- PDGF;NPPDGF;PORCINE PDGF;PDGF, PORCINE PLATELETS;PLATELET-DERIVED GROWTH FACTOR PORCINE;PORCINE PLATELET-DERIVED GROWTH FACTOR;PLATELET-DERIVED GROWTH FACTOR, PORCINE PLATELETS;Platelet-Derived Growth Factor from porcine platelets;Platelet-Derived Growth Factor from human platelets
- CBNumber:
- CB2218223
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00166903
- MOL File:
- Mol file
| storage temp. | -20°C |
|---|---|
| form | lyophilized powder |
| color | white |
| NCI Dictionary of Cancer Terms | PDGF |
NPPDGF price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P8953 | Platelet-Derived Growth Factor from porcine platelets PDGF, lyophilized powder, suitable for cell culture | 5μg | $211.6 | 2024-03-01 | Buy | |
| Sigma-Aldrich | P8147 | Platelet-Derived Growth Factor from human platelets PDGF, lyophilized powder, suitable for cell culture | 1μG | $482 | 2023-01-07 | Buy | |
| Sigma-Aldrich | P8147 | Platelet-Derived Growth Factor from human platelets PDGF, 5 μg/vial, lyophilized powder, suitable for cell culture | 5μG | $1450 | 2023-01-07 | Buy | |
| Sigma-Aldrich | P8147 | Platelet-Derived Growth Factor from human platelets PDGF, 5 μg/vial, lyophilized powder, suitable for cell culture | 1VIAL | $449 | 2022-05-15 | Buy | |
| Usbiological | 357957 | PDGF | 48Tests | $588 | 2021-12-16 | Buy |
NPPDGF Chemical Properties,Uses,Production
Uses
PDGF is a chemoattractant for fibroblasts, smooth muscle cells, monocytes and neutrophils. Also, it acts on fibroblasts and other cells that initiate healing and tissue restoration.
General Description
Platelet-derived growth factor (PDGF) is expressed as homo and heterodimers: PDGF-AB FDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD. The PDGF gene is highly conserved and is mapped to human chromosome 7p22.3. The active form of PDGF exists as disulfide-linked dimers. It consists of cystine-knot-fold growth factor domain, which is highly conserved, except for the N-terminal prodomain, which shows variation in length among the isoforms.
Biochem/physiol Actions
Platelet-derived growth factor (PDGF), not only functions as a growth factor, but also participates in chemotaxis for triggering cell movement. Elevated levels of placental PDGF is observed during the late first and third-trimester pregnancies. PDGF is associated with wound healing. PDGFRα (PDGF receptor α ) phosphorylation, mediated by PDGFA activates pathways associated with cancer. PDGFA has been indicated to induce growth and metastasis in human hepatocellular carcinoma. Vascular endothelial growth factor expression is regulated by PDGF-AA autocrine signaling and is known to promote tumor angiogenesis in vivo. PDGF-BB isomer is found to be critical in angiogenesis and is highly expressed in tumor, mediating oncogenic pericyte recruitment. PDGF-BB is an important regulator of bone homeostasis, repair and regeneration.
NPPDGF Preparation Products And Raw materials
Raw materials
Preparation Products
NPPDGF Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Supplier | Advantage |
|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |