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Larotaxel

CAS No.
156294-36-9
Chemical Name:
Larotaxel
Synonyms
XRP9881;Larotaxel;PNU 100940;Larotaxel USP/EP/BP;Larotaxel (XRP-9881);Thiabendazole Impurity 4;Paclitaxel Impurity 36(Larotaxel);(1S,2S,3R,4S,7R,9S,11R,13R,16S)-4,13-bis(acetyloxy)-16-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-15,18,18-trimethyl-12-oxo-6-oxapentacyclo[12.3.1.03,11.0?,?.0?,11]octadec-14-en-2-yl benzoate;Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (1S,2S,4S,7R,8aR,9aS,10aR,12aS,12bR)-7,12a-bis(acetyloxy)-1-(benzoyloxy)-1,3,4,7,8,9,9a,10,10a,12,12a,12b-dodecahydro-2-hydroxy-5,13,13-trimethyl-8-oxo-2,6-methano-2H-cyclodeca[3,4]cyclopropa[4,5]benz[1,2-b]oxet-4-yl ester, (...
CBNumber:
CB22498816
Molecular Formula:
C45H53NO14
Molecular Weight:
831.9
MDL Number:
MFCD00925691
MOL File:
156294-36-9.mol
Last updated:2023-05-18 11:31:10

Larotaxel Properties

Melting point 170 - 174°C (dec.)
Boiling point 889.3±65.0 °C(Predicted)
Density 1.37
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka 11.20±0.46(Predicted)
color White to Off-White
FDA UNII TWQ8K8A81Y
NCI Drug Dictionary larotaxel

Larotaxel price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC L176000 Larotaxel 156294-36-9 10mg $400 2021-12-16 Buy
Product number Packaging Price Buy
L176000 10mg $400 Buy

Larotaxel Chemical Properties,Uses,Production

Uses

Larotaxel (RPR 109881A) is a taxane analog with a broad spectrum of activity and different toxicity profile and with the possible advantages of surpassing some mechanisms of resistance and penetrating into the CNS.

Larotaxel Preparation Products And Raw materials

Raw materials

Preparation Products

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Larotaxel PNU 100940 XRP9881 Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (1S,2S,4S,7R,8aR,9aS,10aR,12aS,12bR)-7,12a-bis(acetyloxy)-1-(benzoyloxy)-1,3,4,7,8,9,9a,10,10a,12,12a,12b-dodecahydro-2-hydroxy-5,13,13-trimethyl-8-oxo-2,6-methano-2H-cyclodeca[3,4]cyclopropa[4,5]benz[1,2-b]oxet-4-yl ester, (... Larotaxel USP/EP/BP Paclitaxel Impurity 36(Larotaxel) Thiabendazole Impurity 4 Larotaxel (XRP-9881) (1S,2S,3R,4S,7R,9S,11R,13R,16S)-4,13-bis(acetyloxy)-16-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-15,18,18-trimethyl-12-oxo-6-oxapentacyclo[12.3.1.03,11.0?,?.0?,11]octadec-14-en-2-yl benzoate 156294-36-9 Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals API