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Smad3 Inhibitor, SIS3

CAS No.
1009104-85-1
Chemical Name:
Smad3 Inhibitor, SIS3
Synonyms
SIS3 free base;Smad3 Inhibitor;SMAD3 Inhibtor, SIS 3;Smad3 Inhibitor, SIS3;SIS-3 free base,SIS3 free base;(E)-1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-3-pyrrolo[2,3-b]pyridyl)-2-propen-1-one;1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one;2-Propen-1-one, 1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
CBNumber:
CB22520818
Molecular Formula:
C28H27N3O3
Molecular Weight:
453.53
MDL Number:
MFCD24368989
MOL File:
1009104-85-1.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

Smad3 Inhibitor, SIS3 Properties

storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.2 mg/ml
form A crystalline solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Smad3 Inhibitor, SIS3 price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 15945 SMAD3 Inhibitor, SIS3 ≥98% 1009104-85-1 500μg $65 2024-03-01 Buy
Cayman Chemical 15945 SMAD3 Inhibitor, SIS3 ≥98% 1009104-85-1 1mg $121 2024-03-01 Buy
Cayman Chemical 15945 SMAD3 Inhibitor, SIS3 ≥98% 1009104-85-1 5mg $380 2024-03-01 Buy
Usbiological 466177 SMAD3 Inhibtor, SIS 3 1009104-85-1 2.5mg $425 2021-12-16 Buy
TRC S564500 SMAD3Inhibtor,SIS3 1009104-85-1 25mg $820 2021-12-16 Buy
Product number Packaging Price Buy
15945 500μg $65 Buy
15945 1mg $121 Buy
15945 5mg $380 Buy
466177 2.5mg $425 Buy
S564500 25mg $820 Buy

Smad3 Inhibitor, SIS3 Chemical Properties,Uses,Production

Uses

SMAD3 Inhibitor, SIS3 selectively inhibits TGF-β and activin. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.

Definition

ChEBI: An enamide resulting from the formal condensation of the amino group of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline with the carboxy group of (2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acrylic cid.

Smad3 Inhibitor, SIS3 Preparation Products And Raw materials

Raw materials

Preparation Products

Smad3 Inhibitor, SIS3 Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3420 58

1009104-85-1(Smad3 Inhibitor, SIS3)Related Search:

Smad3 Inhibitor Smad3 Inhibitor, SIS3 SIS3 free base SMAD3 Inhibtor, SIS 3 (E)-1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-3-pyrrolo[2,3-b]pyridyl)-2-propen-1-one 2-Propen-1-one, 1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)- SIS-3 free base,SIS3 free base 1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one 1009104-85-1 Specific Inhibitor of Smad3, SIS3