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1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol

1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol Structure
1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol structure
CAS No.
1386439-51-5
Chemical Name:
1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol
Synonyms
SR1555;SR1555 >=98% (HPLC);SR-1555 HCl,SR1555 HCl;1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol;Ethanone, 1-[4-[[4'-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1'-biphenyl]-4-yl]methyl]-1-piperazinyl]-
CBNumber:
CB22751074
Molecular Formula:
C22H22F6N2O2
Molecular Weight:
460.41
MDL Number:
MFCD26142952
MOL File:
1386439-51-5.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
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1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol Properties

Boiling point 527.9±50.0 °C(Predicted)
Density 1.338±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble15mg/mL, clear
form powder
pka 9.19±0.15(Predicted)
color white to beige

SAFETY

Risk and Safety Statements

Hazard statements  H413
WGK Germany  3

1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0765 SR1555 ≥98% (HPLC) 1386439-51-5 5mg $152 2024-03-01 Buy
Sigma-Aldrich SML0765 SR1555 ≥98% (HPLC) 1386439-51-5 25mg $617 2023-01-07 Buy
Product number Packaging Price Buy
SML0765 5mg $152 Buy
SML0765 25mg $617 Buy

1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol Chemical Properties,Uses,Production

Biochem/physiol Actions

SR1555 is a selective RORγ inverse agonist that inhibits the development and function of TH17 cells, a subset of T cells that have been implicated in the pathology of several autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. SR1555 also increases the frequency of T regulatory cells, an effect not seen with previously described RORγ ligands.

1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Sigma-Aldrich 80
DC Chemicals 58
Energy Chemical 58
Beijing Biocreative Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol SR1555 SR1555 >=98% (HPLC) SR-1555 HCl,SR1555 HCl Ethanone, 1-[4-[[4'-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1'-biphenyl]-4-yl]methyl]-1-piperazinyl]- 1386439-51-5