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Mal-PEG1-NHS ester

Mal-PEG1-NHS ester structure

CAS No.: 1807518-72-4

Chemical Name:: Mal-PEG1-NHS ester

Synonyms: Mal-PEG1-SPA;CAS_1807518-72-4;Mal-PEG1-NHS ester;2,5-Dioxopyrrolidin-1-yl 3-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)propanoate;Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester;PROTAC,Antibody-drug conjugates linkers,Inhibitor,inhibit,PROTAC Linkers,Mal-PEG-1-NHS ester,PEG,Linker,ADC Linkers,Mal PEG1 NHS ester,ADC,MalPEG1NHS ester

CBNumber:: CB23062526

Molecular Formula:: C13H14N2O7

Molecular Weight:: 310.26

MDL Number:: MFCD26127783

MOL File:: 1807518-72-4.mol

Last updated:2024-03-27 14:23:05

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Mal-PEG1-NHS ester Properties

Boiling point	488.4±55.0 °C(Predicted)
Density	1.48±0.1 g/cm3(Predicted)
solubility	Soluble in DCM
pka	-2.35±0.20(Predicted)

Mal-PEG1-NHS ester price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
BroadPharm	BP-21854	Mal-PEG1-NHSester 98%	1807518-72-4	100mg	$320	2021-12-16	Buy
BroadPharm	BP-21854	Mal-PEG1-NHSester 98%	1807518-72-4	250mg	$560	2021-12-16	Buy
Apolloscientific	BIPG1502	Mal-PEG1-NHS ester	1807518-72-4	100mg	$623	2021-12-16	Buy
BroadPharm	BP-21854	Mal-PEG1-NHSester 98%	1807518-72-4	500mg	$890	2021-12-16	Buy
ChemScene	CS-0107986	Mal-PEG1-NHSester	1807518-72-4	250mg	$1700	2021-12-16	Buy

Product number	Packaging	Price	Buy
BP-21854	100mg	$320	Buy
BP-21854	250mg	$560	Buy
BIPG1502	100mg	$623	Buy
BP-21854	500mg	$890	Buy
CS-0107986	250mg	$1700	Buy

Mal-PEG1-NHS ester Chemical Properties,Uses,Production

Description

Mal-PEG1-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Biological Activity

Mal-PEG1-NHS ester is a cleavable PEG-based ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Mal-PEG1-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

Mal-PEG1-NHS ester Suppliers

Global( 54)Suppliers

Cleavable

PEGs

Supplier	Tel	Email	Country	ProdList	Advantage
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3149	58
ChemExpress	+86-021-58950125	info@chemexpress.com	China	557	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
Shanghai Huici Pharmaceutical Technology Co., LTD	+8618917134367	lixing@pharmahuici.com	China	133	58
Shanghai Huici Pharmaceutical Technology Co., LTD	+8618917134367	lixing@pharmahuici.com	China	133	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58

Supplier	Advantage
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Wuhan Borenpharm Co., Ltd	58
Hangzhou Huarong Pharm Co., Ltd.	58
ChemExpress	58
Nextpeptide Inc	58
Shanghai Huici Pharmaceutical Technology Co., LTD	58
Shanghai Huici Pharmaceutical Technology Co., LTD	58
LEAPCHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

View Lastest Price from Mal-PEG1-NHS ester manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-03-27	Mal-PEG1-NHS ester 1807518-72-4	US $0.00 / g	1g	>98.00%	1g	Xian confluore Biological Technology Co., Ltd.

Mal-PEG1-NHS ester
1807518-72-4
US $0.00 / g
>98.00%
Xian confluore Biological Technology Co., Ltd.

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Mal-PEG1-NHS ester 2,5-Dioxopyrrolidin-1-yl 3-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)propanoate CAS_1807518-72-4 Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester Mal-PEG1-SPA PROTAC,Antibody-drug conjugates linkers,Inhibitor,inhibit,PROTAC Linkers,Mal-PEG-1-NHS ester,PEG,Linker,ADC Linkers,Mal PEG1 NHS ester,ADC,MalPEG1NHS ester 1807518-72-4 peg