ANTI NGFR P75R
- CAS No.
- Chemical Name:
- ANTI NGFR P75R
- Synonyms
- ANTI-NGFR P75;ANTI NGFR P75R;ANTI-NGFR (HUMAN);ANTI-CD274 (HUMAN);ANTI-P75NTR (HUMAN);ANTI-P75NGFR, HUMAN;ANTI-TNFRSF 16 (HUMAN);ANTI-NGF-RECEPTOR, HUMAN;ANTI-P75 NEUROTROPHIN (HUMAN);ANTI-NERVE GROWTH FACTOR RECEPTOR, P75
- CBNumber:
- CB2313944
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01323986
- MOL File:
- Mol file
ANTI NGFR P75R price More Price(1)
ANTI NGFR P75R Chemical Properties,Uses,Production
Uses
Monoclonal Anti-Nerve Growth Factor Receptor (NGFR p75) may be used:
- for enzyme linked immune sorbent assay (ELISA)
- immunoprecipitation, immunoblotting and immunohistochemistry
- for immunocytochemistry (acetone- or formalin-fixed, Bouin′s solution - or formalin- fixed paraffin-embedded)
- for electron- microscopy radioimmunoassay (RIA) (Kd of 7x10-10 M)
- flow cytometry
- for the inhibition of binding of NGF to the receptor
- for rossette assay
- as a cholinergic immunotoxin
General Description
Recognizes the low affinity human NGFR p75 (also known as gp75NGFR , p75NGFR and p75NTR). The epitope recognized by the antibody exists within the third or fourth cysteine-rich repeats of the NGFR molecule.
Biochem/physiol Actions
Neurotrophins (NT) are growth factors that are essential for the development and maintenance of the nervous system. One of the receptors that mediate the effects of NTs is the Nerve Growth Factor Receptor/TNFRSF16 (p75NGFR, p75NTR). NGFR mediates the effects of NGF that are important in the survival and differentiation of neurons and neural crest-derived cells, during embryonic and early postnatal development. Expression of NGFR has been associated with favorable prognosis and survival in breast and pancreatic cancers.
ANTI NGFR P75R Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI NGFR P75R Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Riedel-de Haen AG | -- | United States | 6825 | 87 | |
| SIGMA-RBI | -- | Switzerland | 6913 | 91 | |
| BIOTREND Chemikalien GmbH | -- | jaeger@biotrend.com | Germany | 6115 | 76 |
| Chemicon Internatinal, Inc. | -- | custserv@chemicon.com | United States | 4175 | 65 |
| Advanced Targeting Systems | -- | ats@atsbio.com | United States | 71 | 71 |
| Alexis Corporation | -- | alexis-ch@alexis-corp.ch | Switzerland | 3599 | 74 |
| Supplier | Advantage |
|---|---|
| Riedel-de Haen AG | 87 |
| SIGMA-RBI | 91 |
| BIOTREND Chemikalien GmbH | 76 |
| Chemicon Internatinal, Inc. | 65 |
| Advanced Targeting Systems | 71 |
| Alexis Corporation | 74 |