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3,6-DIOXAOCTANEDIOIC ACID

CAS No.
23243-68-7
Chemical Name:
3,6-DIOXAOCTANEDIOIC ACID
Synonyms
DOODA;PEG2-(CH2CO2H)2;3,6-Dioxasuberic acid;HOOCCH2O-PEG1-CH2COOH;3, 6-dioxyoctaneic acid;3,6-dioxoctanedioic acid;3,6-Dioxaoctandioic acid;(Ethylenebisoxy)diacetic acid;1,2-Bis(carboxymethoxy)ethane;3,6-Dioxaoctanedioic acid CAS
CBNumber:
CB2499237
Molecular Formula:
C6H10O6
Molecular Weight:
178.14
MDL Number:
MFCD00054502
MOL File:
23243-68-7.mol
Last updated:2023-04-23 13:52:06

3,6-DIOXAOCTANEDIOIC ACID Properties

Melting point 68-71℃
Boiling point 429.2±25.0 °C(Predicted)
Density 1.375
vapor pressure 0Pa at 20℃
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 3.09±0.10(Predicted)
form solid
color White to off-white
LogP -2.29 at 25℃
FDA UNII 2ZVS8WS40O

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H332-H315-H319-H335
Precautionary statements  P260-P280-P312
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45-27-22
RIDADR  3261
HazardClass  8
PackingGroup  III
HS Code  2917198090

3,6-DIOXAOCTANEDIOIC ACID price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D486153 3,6-DioxaoctanedioicAcid 23243-68-7 500mg $110 2021-12-16 Buy
Apolloscientific OR19555 3,6-Dioxaoctanedioicacid 23243-68-7 1g $44 2021-12-16 Buy
SynQuest Laboratories 2121-1-37 3,6-Dioxaoctanedioic acid 23243-68-7 1g $48 2021-12-16 Buy
Biosynth Carbosynth FD154915 3,6-Dioxaoctanedioic acid 23243-68-7 500mg $65 2021-12-16 Buy
Activate Scientific AS35298 3,6-Dioxaoctanedioic acid 95+% 23243-68-7 1g $86 2021-12-16 Buy
Product number Packaging Price Buy
D486153 500mg $110 Buy
OR19555 1g $44 Buy
2121-1-37 1g $48 Buy
FD154915 500mg $65 Buy
AS35298 1g $86 Buy

3,6-DIOXAOCTANEDIOIC ACID Chemical Properties,Uses,Production

Uses

3,6-Dioxaoctanedioic Acid (cas# 23243-68-7) is a useful research chemical.

Description

PEG2-(CH2CO2H)2 is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

3,6-Dioxaoctanedioic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Uses

3,6-Dioxaoctanedioic Acid is a useful reagent for the preparation of degradation agents for cyclin dependent kinase.

Flammability and Explosibility

Not classified

Synthesis

Synthesis_23243-68-7
To 15 ml (0.33 mol) of nitric acid was added at 45??C while stirring 1 g of diethylene glycol from the overall amount of 5.9 g (0.06 mol), and the mixture was heated to 65??C. After the end of nitrogen oxides evolution and cooling the mixture to 45-50??C another portion of diethylene glycol was added. Overall time of the reagent addition to the reaction mixture was 1 h. The mixture was kept at 45??C for 40 min and then it was heated at 80??C for 30 min. The solvent was removed in a vacuum at 70??C, the residue was dried by azeotropic distillation with benzene using Dean-Stark trap, then the product was fi ltered off and recrystallized from acetone-benzene mixture. 3,6-Dioxaoctanedioic acid (VIII) was similarly obtained. Yield 7.3 g (89%), colorless crystals. Rf 0.20 (E), mp 76-77??C (mp 75-76??C [13]). IR spectrum, |í, cm-1: 3167 (OH), 2914 (CH), 1733 (C=O acid), 1410, 1229 (C-O), 1121 (C-O). Mass spectrum, m/z (Irel, %): 178.5 [M]+ (76), 200.9 (55), 216.8 (46).

79-11-8
112-27-6
23243-68-7
Synthesis of 3,6-DIOXAOCTANEDIOIC ACID from Chloroacetic acid and Triethylene glycol

3,6-DIOXAOCTANEDIOIC ACID Preparation Products And Raw materials

Global( 119)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Rlavie Technology Co ltd
+86-021-67759270 +8617717059219 sales@rlavie.com China 1030 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15956 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21688 55
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58

View Lastest Price from 3,6-DIOXAOCTANEDIOIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,6-DIOXAOCTANEDIOIC ACID pictures 2024-01-23 3,6-DIOXAOCTANEDIOIC ACID
23243-68-7
US $0.00 / KG 1KG 98% 1000KG /month Shanghai Daken Advanced Materials Co.,Ltd
3, 6-dioxyoctaneic acid pictures 2022-09-01 3, 6-dioxyoctaneic acid
23243-68-7
US $0.00-0.00 / g 10g 95% 10kg Zhengzhou Gecko Scientific Inc.
3,6-Dioxaoctanedioic acid pictures 2022-01-04 3,6-Dioxaoctanedioic acid
23243-68-7
US $0.00-0.00 / KG 1g 97%minHNMR 50kgs/month Shanghai Rlavie Technology Co ltd
3,6-Dioxasuberic acid Acetic acid, 2,2'-[1,2-ethanediylbis(oxy)]bis- (Triglycolic acid) Acetic acid, 2,2‘-[1,2-ethanediylbis(oxy)]bis- (2-CARBOXYMETHOXYETHOXY)ACETIC ACID 2,2'-(Ethane-1,2-diylbis(oxy))diacetic acid 3,6-dioxoctanedioic acid PEG2-(CH2CO2H)2 2-[2-(Carboxymethyloxy)ethoxy]acetic acid 2,2'-[ethylenebis(oxy)] bisacetic acid for synthesis 2,2'-[ethylenebis(oxy)]bisacetic acid 2,2′-(Ethylenbis(oxy))bisessigsure 3,6-Dioxaoctandioic acid (Ethylenebisoxy)diacetic acid 2,2'-(Ethylenebisoxy)diacetic acid 2,2'-[1,2-Ethanediylbis(oxy)]diacetic acid 1,2-Bis(carboxymethoxy)ethane 2,5-Dioxa-1,6-hexanedicarboxylic acid 3,6-Dioxaoctane-1,8-dioic acid 3,6-Dioxaoctanedioic acid CAS 3,6-dioxa-1,8-octanedioic acid HOOCCH2O-PEG1-CH2COOH 2-[2-(carboxymethoxy)ethoxy]aceticaci DOODA 3, 6-dioxyoctaneic acid HOOCCH2O-PEG1-CH2COOH/Acetic acid, 2,2'-[1,2-ethanediylbis(oxy)]bis- 23243-68-7 -CH2OCH2CO2H2 peg