DADEPYLIPQQG
- CAS No.
- Chemical Name:
- DADEPYLIPQQG
- Synonyms
- EGFR;DADEPYLIPQQG;EGFR (988-998);DADEY(PO3)LIPQQG;Mouse Anti-EGFR antibody;Rat EGFR Protein, His Tag;Mouse EGFR Protein, Fc Tag;Human EGFR Protein, Fc Tag;Mouse EGFR Protein, His Tag;Human EGFR Protein, His Tag
- CBNumber:
- CB2770154
- Molecular Formula:
- C54H82N13O24P
- Molecular Weight:
- 1328.28
- MDL Number:
- MFCD00928891
- MOL File:
- Mol file
| storage temp. | -20°C |
|---|---|
| form | lyophilized powder |
| color | white |
| NCI Dictionary of Cancer Terms | EGFR |
DADEPYLIPQQG price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E3641 | Epidermal Growth Factor Receptor human buffered aqueous glycerol solution, 5,000-30,000?units/mg protein (Lowry) | 500units | $759 | 2024-03-01 | Buy | |
| Sigma-Aldrich | E2645 | Epidermal Growth Factor Receptor human lyophilized powder, ≥15,000?units/mg protein (Bradford) | 500UNITS | $586 | 2023-06-20 | Buy | |
| Usbiological | 369876 | EGFR | 48Tests | $588 | 2021-12-16 | Buy | |
| Usbiological | 382729 | EGFR | 96Tests | $669 | 2021-12-16 | Buy | |
| Usbiological | 472035 | EGFR | 96Tests | $731 | 2021-12-16 | Buy |
DADEPYLIPQQG Chemical Properties,Uses,Production
General Description
Epidermal growth factor receptor (EGFR) belongs to a family of cell surface receptors called receptor tyrosine kinases (RTKs), and is also the most studied member of this family. It is made up of an ectodomain (ECD), which contains four subdomains called DI-DIV, a transmembrane region, and a cytoplasmic tyrosine kinase domain (TKD). Binding of the ligand induces conformational changes in the ECD, which leads to the dimerization of EGFR. This results in the activation of the TKD, and the subsequent signal transduction. This receptor has a molecular weight of ～178kDa.
Biochem/physiol Actions
EGF exerts its actions by binding to the EGF receptor (EGFR), a 170 kDa glycoprotein having EGF-activated protein tyrosine kinase activity. Even in the absence of EGF-like ligands, EGFR can participate in cellular responses elicited by several other stimuli. High levels of EGFR are expressed in approximately one third of human epithelial tumors, and in the cancers of the bladder, breast or lung that have poor clinical prognosis, hence the interest in targeting EGFR.
DADEPYLIPQQG Preparation Products And Raw materials
Raw materials
Preparation Products
DADEPYLIPQQG Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29797 | 68 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 15926423062 | 422450190@qq.com | China | 10132 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 6633 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| Shanghai Toyang Biotechnology Co., LTD | 021-59555769 13524932310 | 1405894150@qq.com | China | 8221 | 58 |
| Beijing Boorsen Biotechnology Co., Ltd | 400-901-9800 18611424007 | cis@bioss.com.cn | China | 9518 | 58 |