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c-Fms-IN-9

c-Fms-IN-9 structure

CAS No.: 1628574-50-4

Chemical Name:: c-Fms-IN-9

Synonyms: c-Fms-IN-9;cFmsIN9,c Fms IN 9;3H-1,2,4-Triazol-3-one, 5-(1,1-dimethylethyl)-1,2-dihydro-2-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-

CBNumber:: CB28054340

Molecular Formula:: C21H23N7O2

Molecular Weight:: 405.45

MDL Number:: MFCD32067991

MOL File:: 1628574-50-4.mol

Last updated:2023-05-21 10:59:17

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c-Fms-IN-9 Properties

Density	1.32±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
pka	8.97±0.20(Predicted)

c-Fms-IN-9 Chemical Properties,Uses,Production

Description

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1]. c-FMS[1]

c-Fms-IN-9 inhibits M-NFS-60, THP-1 and osteoclast cells proliferation with IC50s of 0.01-0.1 μM[1].

References

[1]. Gary E. L. BRANDT, et al. 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145023A1.

c-Fms-IN-9 Preparation Products And Raw materials

Raw materials

Preparation Products

c-Fms-IN-9 Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7892	56
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
TargetMol Chemicals Inc.	58

c-Fms-IN-9 cFmsIN9,c Fms IN 9 3H-1,2,4-Triazol-3-one, 5-(1,1-dimethylethyl)-1,2-dihydro-2-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]- 1628574-50-4