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TL02-59 dihydrochloride

CAS No.
2415263-06-6
Chemical Name:
TL02-59 dihydrochloride
Synonyms
TL02-59 dihydrochloride;TL0259 dihydrochloride,TL-02-59 dihydrochloride,TL02 59 dihydrochloride
CBNumber:
CB28054562
Molecular Formula:
C32H35ClF3N5O4
Molecular Weight:
646.11
MDL Number:
MFCD34470292
MOL File:
2415263-06-6.mol
Last updated:2023-06-30 15:45:59

TL02-59 dihydrochloride Properties

solubility Soluble to 50 mM in DMSO

TL02-59 dihydrochloride Chemical Properties,Uses,Production

Biological Activity

TL 0259 is a selective and highly potent Fgr and Lyn inhibitor (IC50 values are 0.03 and 0.1 nM, respectively). Exhibits selectivity for Fgr and Lyn over other Src family kinases and other nonreceptor and receptor tyrosine kinases. Suppresses proliferation of acute myelogenous leukemia (AML) cell lines in vitro. Eliminates leukemic cells from spleen and bone of mice bearing AML xenografts. Orally bioavailable.

storage

Store at -20°C

TL02-59 dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

TL02-59 dihydrochloride Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 18108052721 2850505130@qq.com China 5182 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
TL02-59 dihydrochloride TL0259 dihydrochloride,TL-02-59 dihydrochloride,TL02 59 dihydrochloride 2415263-06-6