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(S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-

CAS No.
101328-84-1
Chemical Name:
(S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-
Synonyms
Levosimendan isomer;Levosimendan Impurity 17;(S)-6-(4-aMinophenyl)-5-Methyl-4,5-dihydropyridazin-3(2H)-one;(5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone;(S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-;3(2H)-Pyridazinone, 6-(4-aMinophenyl)-4,5-dihydro-5-Methyl-, (5S)-
CBNumber:
CB2949136
Molecular Formula:
C11H13N3O
Molecular Weight:
203.24
MDL Number:
MFCD31562185
MOL File:
101328-84-1.mol
MSDS File:
SDS
Last updated:2023-05-12 11:12:40

(S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl- Chemical Properties,Uses,Production

Uses

(5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone is an intermediate in the synthesis of Dextrosimendan (D299550), an isomer and impurity of Levosimendan (L378000), a bioactive enantiomer of Simendan (S466000). Levosimendan is a positive inotropic agent with vasodilating activity.

139128-27-1
101328-84-1
Synthesis of (S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl- from Acetamide, N-[4-[(4S)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]-

(S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl- Suppliers

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(S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl- 3(2H)-Pyridazinone, 6-(4-aMinophenyl)-4,5-dihydro-5-Methyl-, (5S)- (S)-6-(4-aMinophenyl)-5-Methyl-4,5-dihydropyridazin-3(2H)-one Levosimendan Impurity 17 (5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone Levosimendan isomer 101328-84-1