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ChemicalBook >> CAS DataBase List >>5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl-

5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl-

5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl- Structure
5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl- structure
CAS No.
1241046-32-1
Chemical Name:
5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl-
Synonyms
QM295;5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl-
CBNumber:
CB312662477
Molecular Formula:
C17H13NO4
Molecular Weight:
295.29
MDL Number:
MOL File:
1241046-32-1.mol
Last updated:2025-08-21 16:37:02
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5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl- Properties

Boiling point 456.5±55.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
form Solid
pka -7.70±0.60(Predicted)
color Light yellow to yellow

5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl- Chemical Properties,Uses,Production

Uses

QM295 is an endoplasmic reticulum oxidation 1 (ERO1) inhibitor with selectively reversible thiol reactivity. QM295 can be used for the research of endoplasmic reticulum stress[1].

in vivo

QM295 (50 μM, 30 min) has the accumulation of an ERO1α form with lower mobility in vivo[1].

References

[1] Jaime D Blais, et al. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J Biol Chem. 2010 Jul 2;285(27):20993-1003. DOI:10.1074/jbc.M110.126599

5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl- Preparation Products And Raw materials

Raw materials

Preparation Products

5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39035 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 8011 55
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29257 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

View Lastest Price from 5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
QM295 pictures 2025-08-21 QM295
1241046-32-1
 US $48.00 / mg 10g TargetMol Chemicals Inc.
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    1241046-32-1
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5(2H)-Isoxazolone, 4-[(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-3-phenyl- QM295 1241046-32-1