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Adenanthin

Adenanthin structure

CAS No.: 111917-59-0

Chemical Name:: Adenanthin

Synonyms: Adenanthin;Actinodephnine Acuminatin Acuminatoside Adenanthin;Kaur-16-ene-6,15-dione, 1,7,11-tris(acetyloxy)-3-hydroxy-, (1α,3β,7β,11β)-;Kaur-16-ene-6,15-dione,1,7,11-tris(acetyloxy)-3-hydroxy-, (1a,3b,7b,11b)- (9CI)

CBNumber:: CB31267733

Molecular Formula:: C26H34O9

Molecular Weight:: 490.55

MDL Number:: MFCD20260622

MOL File:: 111917-59-0.mol

MSDS File:: SDS

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Adenanthin Properties

Boiling point	593.4±50.0 °C(Predicted)
Density	1.29±0.1 g/cm3(Predicted)
pka	14.13±0.70(Predicted)

Adenanthin price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Arctom	CFN99215	Adenanthin	111917-59-0	5mg	$498	2021-12-16	Buy
Crysdot	CD32002839	Adenanthin 97%	111917-59-0	5mg	$930	2021-12-16	Buy

Product number	Packaging	Price	Buy
CFN99215	5mg	$498	Buy
CD32002839	5mg	$930	Buy

Adenanthin Chemical Properties,Uses,Production

Enzyme inhibitor

This diterpenoid (FW = 484.63 g/mol; CAS 111917-59-0) from the leaves of Rabdosia adenantha, induces differentiation of acute promyelocytic leukemia (APL) cells. Adenanthin targets the conserved cysteine thiols of peroxiredoxins I and II (or Prx I and Prx II), inhibiting their peroxidase activities and consequently increasing cellular hydrogen peroxide. The latter leads to the activation of Extracellular signal-Regulated Kinases (ERKs) and increased transcription of CCAAT/enhancer-binding protein β (or C/EBPs), further contributing to differentiation. Adenanthin induces APL-like cell differentiation, represses tumor growth in vivo and prolongs the survival of mouse APL models that are sensitive and resistant to retinoic acid.

Adenanthin Preparation Products And Raw materials

Raw materials

Preparation Products

Adenanthin Suppliers

Global( 60)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aktin Chemicals, Inc.	028-85159085	info@aktinchem.com	CHINA	1025	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19994	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	6011	61
BioBioPha Co., Ltd.	0871-65217109 13211707573;	y.liu@mail.biobiopha.com	China	5654	65
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7892	56

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
Shaanxi Pioneer Biotech Co., Ltd .	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Aktin Chemicals, Inc.	58
Labnetwork lnc.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Chembest Research Laboratories Limited	61
BioBioPha Co., Ltd.	65
Sichuan Wei Keqi Biological Technology Co., Ltd.	56

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Adenanthin Actinodephnine Acuminatin Acuminatoside Adenanthin Kaur-16-ene-6,15-dione,1,7,11-tris(acetyloxy)-3-hydroxy-, (1a,3b,7b,11b)- (9CI) Kaur-16-ene-6,15-dione, 1,7,11-tris(acetyloxy)-3-hydroxy-, (1α,3β,7β,11β)- 111917-59-0