Monoclonal Anti-Human IgG (Fc specific)

CAS No.
Chemical Name:
Monoclonal Anti-Human IgG (Fc specific)
Synonyms
Monoclonal Anti-Human IgG (Fc specific);Monoclonal Anti-Human IgG (Fc specific)-FITC antibody produced in mouse;Monoclonal Anti-Human IgG (Fc specific)-Biotin antibody produced in mouse
CBNumber:
CB32089932
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Monoclonal Anti-Human IgG (Fc specific) Properties

storage temp. −20°C

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
Risk Statements  21/22
Safety Statements  36/37

Monoclonal Anti-Human IgG (Fc specific) Chemical Properties,Uses,Production

Uses

Monoclonal Anti-Human IgG (Fc specific)-FITC antibody produced in mouse has been used in:

  • Fluorescent Dot Immunobinding Assay (F-DIBA)
  • Particle Immunofluorescent Assay (F-IFMA)
  • flow cytometry

General Description

Monoclonal Anti-Human IgG (mouse IgG2a isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Immunoglobulins (Igs) belongs immunoglobulin super-family. Each immunoglobin have two heavy (H) and two light (L), held together by disulphide linkages. The light comprises of one variable N-terminal region and a constant C-terminal region. The heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region.

Biochem/physiol Actions

Digestion of IgG by papain results in generation of fragment antigen binding (Fab) comprising one complete L chain and a variable and CH1 region of H chain. Pepsin digestion of IgG results in fragment crystallisable (fc), containing the H chain constant region. IgG antibody have enormous therapeutic potential and the Fc is for the development of therapeutic antibody. Although the antibody site is located in the terminal end of the human IgG molecule (part of the Fab fragment), the Fc portion has various important functions such as complement fixation, site for rheumatoid factor (autoantibodies directed to Fc), passage through placental membrane and staphylococcus protein A binding.

Monoclonal Anti-Human IgG (Fc specific) Preparation Products And Raw materials

Raw materials

Preparation Products

Monoclonal Anti-Human IgG (Fc specific) Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Monoclonal Anti-Human IgG (Fc specific) Monoclonal Anti-Human IgG (Fc specific)-Biotin antibody produced in mouse Monoclonal Anti-Human IgG (Fc specific)-FITC antibody produced in mouse