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4-Cholesten-3-one

4-Cholesten-3-one structure

CAS No.: 601-57-0

Chemical Name:: 4-Cholesten-3-one

Synonyms: CHOLESTENONE;4-Cholestenone;4-CHOLESTEN-3-ONE;3-Oxocholest-4-ene;3-OXO-4-CHOLESTENE;cholest-4-en-3-one;4-Cholestene-3-one;CHOLEST-4-ENE-3-ONE;3-KETO-4-CHOLESTENE;(+)-4-CHOLESTEN-3-ONE

CBNumber:: CB3222827

Molecular Formula:: C27H44O

Molecular Weight:: 384.64

MDL Number:: MFCD00003663

MOL File:: 601-57-0.mol

MSDS File:: SDS

Last updated:2023-11-03 16:33:47

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4-Cholesten-3-one Properties

Melting point	79-82 °C
alpha	92.5 º (c=2, CHCl3)
Boiling point	451.27°C (rough estimate)
Density	0.9717 (rough estimate)
refractive index	1.5100 (estimate)
storage temp.	-20°C
solubility	Chloroform (Sparingly), Methanol (Slightly, Heated)
form	Solid
color	White to Off-White
optical activity	[α]23/D +91.0°, c = 2 in chloroform
Water Solubility	<0.5 g/L
BRN	4707774
Stability	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	601-57-0(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	7T94NHD99C
NIST Chemistry Reference	Cholest-4-en-3-one(601-57-0)
EPA Substance Registry System	Cholest-4-en-3-one (601-57-0)

SAFETY

Risk and Safety Statements

Hazard statements

H413

Hazard Codes

Risk Statements

36/37/38

Safety Statements

22-24/25-36-26

WGK Germany

RTECS

FZ7700000

TSCA

Yes

HS Code

29142900

NFPA 704

	1
1		0

4-Cholesten-3-one price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	188174	(+)-4-Cholesten-3-one 98%	601-57-0	1g	$33	2024-03-01	Buy
Sigma-Aldrich	188174	(+)-4-Cholesten-3-one 98%	601-57-0	10g	$313	2024-03-01	Buy
Alfa Aesar	A11743	4-Cholesten-3-one, 98+%	601-57-0	5g	$71.65	2024-03-01	Buy
Alfa Aesar	A11743	4-Cholesten-3-one, 98+%	601-57-0	25g	$253.65	2024-03-01	Buy
Cayman Chemical	25713	Cholestenone	601-57-0	5g	$81	2024-03-01	Buy

Product number	Packaging	Price	Buy
188174	1g	$33	Buy
188174	10g	$313	Buy
A11743	5g	$71.65	Buy
A11743	25g	$253.65	Buy
25713	5g	$81	Buy

4-Cholesten-3-one Chemical Properties,Uses,Production

Description

Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol. It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 μg/ml. Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland. It has been used as synthetic intermediate in the synthesis of steroids.

Chemical Properties

white to light yellow crystals or powder

Uses

4-Cholesten-3-one is used as a chiral building block for proteomics research. It is an intestinal metabolite of cholesterol and exhibits an anti-obesity effect on animals.

Definition

ChEBI: Cholest-4-en-3-one is a cholestanoid that is cholest-4-ene substituted by an oxo group at position 3. It has a role as a human metabolite and a plant metabolite. It is a cholestanoid and a 3-oxo-Delta(4) steroid.

General Description

Cholestenone is a cholesterol metabolite and analog, which substitutes membrane cholesterol and elevates membrane fluidity.

4-Cholesten-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

5ALPHA-CHOLESTAN-3-ONE DELTA-4,6-CHOLESTADIENOL (30 MG)

4-Cholesten-3-one Suppliers

Global( 179)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12468	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	6710	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Standard Technology Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Career Henan Chemica Co	58
Shanghai UCHEM Inc.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Nanjing Doge Biomedical Technology Co., Ltd	58

View Lastest Price from 4-Cholesten-3-one manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-11-04	4-Cholesten-3-one 601-57-0	US $20.00-1.00 / kg	1kg	0.99	20 tons	Hebei Yanxi Chemical Co., Ltd.
2023-10-10	4-Cholesten-3-one 601-57-0	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-09-06	4-Cholesten-3-one 601-57-0	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.

4-Cholesten-3-one
601-57-0
US $20.00-1.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

4-Cholesten-3-one
601-57-0
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

4-Cholesten-3-one
601-57-0
US $0.00-0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

4-Cholesten-3-one Spectrum

4-Cholesten-3-one(601-57-0)MS 4-Cholesten-3-one(601-57-0)¹HNMR 4-Cholesten-3-one(601-57-0)¹³CNMR 4-Cholesten-3-one(601-57-0)IR1 4-Cholesten-3-one(601-57-0)IR2 4-Cholesten-3-one(601-57-0)Raman

601-57-0(4-Cholesten-3-one)Related Search:

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Androstenedione Dimethyl ether 2BETA,3BETA,14ALPHA,22[R],25-PENTAHYDROXY-7-CHOLESTEN-6-ONE,2β,3β,14α,22(r),25-pentahydroxy-7-cholesten-6-one

1of4

17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecah 17-(1,5-DIMETHYLHEXYL)-10,13-DIMETHYL-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-ONE (+)-4-CHOLESTEN-3-ONE 4-CHOLESTEN-3-ONE 3-KETO-4-CHOLESTENE (+)-3-OXO-4-CHOLESTENE 3-OXO-4-CHOLESTENE CHOLEST-4-ENE-3-ONE CHOLESTENONE 3-Oxocholest-4-ene 4-Cholestenone cholest-4-en-3-one delta4-Cholesten-3-one (8S,9S,10R,13R,14S,17R)-17-((R)-1,5-DIMETHYL-HEXYL)-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE 10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one 4-CHOLESTEN-3-ONE, 98+% (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one 3-Keto-4-cholestene, 3-Oxo-4-cholestene 3-Keto-4-cholestene, 3-Oxo-4-cholestene, 4-Cholesten-3-one delta(sup 4)-Cholestenone (20R)-Cholesta-4-ene-3-one Cholestane-4-ene-3-one (8S,9S,10R,13R,14S,17R)-10,13-diMethyl-17-((R)-6-Methylheptan-2-yl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (+)-4-Cholesten-3-one 98% 4-CHOLESTEN-3-ONE;CHOLESTENONE (1S,2R,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one 4-Cholestene-3-one (+)-4-Cholesten-3-one > (+)-4-Cholesten-3-one (+)-3-Oxo-4-Cholestene 601-57-0 Complex Molecules Chiral Building Blocks Asymmetric Synthesis Steroids Steroids (Others) Steroids Steroids (Others) Biochemistry