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β-Hydroxy Thyroxine

CAS No.
107849-54-7
Chemical Name:
β-Hydroxy Thyroxine
Synonyms
Thyroxine Impurity 1;β-Hydroxy Thyroxine;Beta-Hydroxy Thyroxine;Levothyroxine Impurity 2;Levothyroxine Impurity 21;Thyroxine, β-hydroxy- (7CI);Levothyroxine USP Impurity A;Levothyroxine beta-Hydroxy Impurity;Levothyroxine beta-Hydroxy Impurity 2;β-[3,5-Diiodo-4-(3,5-diiodo-4-hydroxyphenoxy)phenyl]serine
CBNumber:
CB32551088
Molecular Formula:
C15H11I4NO5
Molecular Weight:
792.87
MDL Number:
MOL File:
107849-54-7.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

β-Hydroxy Thyroxine Properties

Melting point >175°C (dec.)
Boiling point 627.4±55.0 °C(Predicted)
Density 2.706±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 1.97±0.34(Predicted)
color White to Pale Beige
FDA UNII 9H1713CTRY

β-Hydroxy Thyroxine price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H972215 O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-b-hydroxy-L-tyrosine 107849-54-7 2.5mg $1265 2021-12-16 Buy
American Custom Chemicals Corporation AAA0017232 BETA-HYDROXY THYROXINE 95.00% 107849-54-7 5MG $502.02 2021-12-16 Buy
American Custom Chemicals Corporation AAA0017232 BETA-HYDROXY THYROXINE 95.00% 107849-54-7 10MG $639 2021-12-16 Buy
Product number Packaging Price Buy
H972215 2.5mg $1265 Buy
AAA0017232 5MG $502.02 Buy
AAA0017232 10MG $639 Buy

β-Hydroxy Thyroxine Chemical Properties,Uses,Production

Uses

O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-b-hydroxy-L-tyrosine is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia.

Uses

It has been prepared for testing as possible antithyroid. It showed some thyromimetic activity.

β-Hydroxy Thyroxine Preparation Products And Raw materials

Raw materials

Preparation Products

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β-Hydroxy Thyroxine β-[3,5-Diiodo-4-(3,5-diiodo-4-hydroxyphenoxy)phenyl]serine Levothyroxine beta-Hydroxy Impurity Beta-Hydroxy Thyroxine Levothyroxine Impurity 21 Thyroxine, β-hydroxy- (7CI) Levothyroxine Impurity 2 Levothyroxine USP Impurity A Thyroxine Impurity 1 Levothyroxine beta-Hydroxy Impurity 2 O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-β-hydroxy-L-tyrosine 107849-54-7 C15H11I4NO5 Aromatics, Amino Acids & Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals Amino Acids & Derivatives Aromatics Intermediates & Fine Chemicals Pharmaceuticals