ChemicalBook >> CAS DataBase List >>MK-2048
MK-2048
- CAS No.
- 870005-19-9
- Chemical Name:
- MK-2048
- Synonyms
- CS-235;MK-2048;(6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl;(6S)-2-[(3-chloro-4-fluorophenyl)Methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-Methyl-1,9-dioxo-;(6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxam;(6S)-2-[(3-chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide;Pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, 2-[(3-chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-, (6S)-
- CBNumber:
- CB32570375
- Molecular Formula:
- C22H23ClFN5O4
- Molecular Weight:
- 475.9
- MDL Number:
- MOL File:
- 870005-19-9.mol
Last updated:2023-04-23 13:52:06
| Melting point | >240°C (dec.) |
|---|---|
| Density | 1.52±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 6.52±0.40(Predicted) |
| form | Solid |
| color | Yellow |
| FDA UNII | 2V3GK8VNG6 |
MK-2048 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 017697 | MK-2048 | 870005-19-9 | 5mg | $566 | 2021-12-16 | Buy |
| AK Scientific | Y0373 | Pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide,2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-N,6-dimethyl-1,9-dioxo-,(6S)- | 870005-19-9 | 5g | $10040 | 2021-12-16 | Buy |
MK-2048 Chemical Properties,Uses,Production
Uses
MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.
MK-2048 Preparation Products And Raw materials
Raw materials
Preparation Products
MK-2048 Suppliers
Global( 28)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
| ApexBio Technology LLC | +1-832-696-8203 | info@apexbt.com | United States | 477 | 60 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9798 | 50 |
| Shanghai Changyan Chem & Tech Co., Ltd. | 021-021-20242659 18930833303 | order@changyanchem.com | China | 5008 | 55 |
| Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 | sales@chemrenpharm.com | China | 3553 | 58 |
| Cckinase, Inc. | +1 (732)236-3202 | sales@cckinase.com | United States | 2738 | 58 |
| Wuhan Yanzhe Technology Co., Ltd | 15527250409 | wenhaotian12@163.com | China | 4576 | 58 |
| Shanghai tingchong biology science and technology co., ltd | 18964309092 18964309092 | 2769493375@qq.com | China | 2635 | 58 |
MK-2048
(6S)-2-[(3-chloro-4-fluorophenyl)Methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-Methyl-1,9-dioxo-
(6S)-2-[(3-chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide
(6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl
CS-235
Pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, 2-[(3-chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-, (6S)-
(6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxam
870005-19-9
C22H23ClFN5O4
Inhibitor