(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy

CAS No.
1246298-66-7
Chemical Name:
(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy
Synonyms
7-dihydroxy-5-cholestenoic acid;3β,7β-dihydroxy -5-cholestenoic acid;3ss,7ss-dihydroxy-5-cholestenoic acid;(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy;(25R)-cholest-5-en-26-oic acid, 3β,7β-hydroxy;(25R) - Cholester-5-ene-26-oleic acid, 3?, 7- hydroxyl;Cholest-5-en-26-oic acid, 3,7-dihydroxy-, (3β,7β,25R)-;(25R)-CHOLEST-5-EN-26-OIC ACID, 3,7-HYDROXY;3;7-DIHYDROXY-5-CHOLESTENOIC ACID
CBNumber:
CB32719909
Molecular Formula:
C27H44O4
Molecular Weight:
432.63586
MDL Number:
MOL File:
1246298-66-7.mol

(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy Properties

Boiling point 588.1±35.0 °C(Predicted)
Density 1.12±0.1 g/cm3(Predicted)
pka 4.81±0.21(Predicted)

(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy Chemical Properties,Uses,Production

Uses

3β,7β-dihydroxy-5-cholestenoic acid may be used as an authentic diastereoisomer standard in mass spectrometry (MS) experiments.

General Description

3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) is associated with plasma and is a C27 acid. 3β,7β-diHCA is synthesized from 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid (3βH,7O-CA) by the action of the enzyme hydroxysteroid 11-β dehydrogenase 1.

Biochem/physiol Actions

3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) levels are elevated in Niemann-Pick type C (NPC) disease and Niemann-Pick (NP) disease type B disorders. It elicits toxicity to oculomotor neurons.

(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy Preparation Products And Raw materials

Raw materials

Preparation Products

(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy Suppliers

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Creative Enzymes
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Codow Chemical Co.,Ltd. 18620099427 amy@howeipharm.com China 17698 55
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SHANGHAI ZZBIO CO., LTD. 15102117276 18019707223 tech@zzbioco.com China 12065 58
(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy (25R)-CHOLEST-5-EN-26-OIC ACID, 3,7-HYDROXY;3;7-DIHYDROXY-5-CHOLESTENOIC ACID 7-dihydroxy-5-cholestenoic acid 3ss,7ss-dihydroxy-5-cholestenoic acid Cholest-5-en-26-oic acid, 3,7-dihydroxy-, (3β,7β,25R)- (25R) - Cholester-5-ene-26-oleic acid, 3?, 7- hydroxyl (25R)-cholest-5-en-26-oic acid, 3β,7β-hydroxy 3β,7β-dihydroxy -5-cholestenoic acid 1246298-66-7