Anti-Indoleamine 2,3-dioxygenase
- CAS No.
- Chemical Name:
- Anti-Indoleamine 2,3-dioxygenase
- Synonyms
- Anti-IDO;Anti-IDO1;Anti-Ido2;Anti-3-dioxygenase 2;Anti-Indoleamine 2,3-dioxygenase;Anti-Indoleamine 2,3-dioxygenase 1;Anti-IDO1 antibody produced in rabbit;Anti-Indoleamine-pyrrole 2,3-dioxygenase;Anti-INDO (6-20) antibody produced in rabbit;Anti-INDO (136-150) antibody produced in rabbit
- CBNumber:
- CB32885406
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01864612
- MOL File:
- Mol file
Anti-Indoleamine 2,3-dioxygenase price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | HPA023149 | Anti-IDO1 antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution, Ab2 | 25μL | $294 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB3701447 | Monoclonal Anti-IDO2 antibody produced in mouse clone 1HC, purified immunoglobulin | 100μG | $531 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA023149 | Anti-IDO1 antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution, Ab2 | 100μL | $514 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA027772 | Anti-IDO1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3 | 25μL | $282 | 2023-06-20 | Buy | |
Sigma-Aldrich | HPA027772 | Anti-IDO1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3 | 100μL | $547 | 2023-06-20 | Buy |
Anti-Indoleamine 2,3-dioxygenase Chemical Properties,Uses,Production
Uses
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
IDO1 (indoleamine 2,3-dioxygenase 1) protein is present in the cytoplasm and exists as a monomer. It is mainly expressed in parenchymal tissues including, lungs, gut and the fetal-maternal unit during pregnancy. In addition, it can be seen in trophoblast, fibroblasts, epithelial and tumor cells, tumor-associated cells, macrophages, dendritic cells and microglial cells in the central nervous system. The gene is mapped to human chromosome 8p11. It is also referred to as INDO (indoleamine-pyrrole 2,3-dioxygenase).
Biochem/physiol Actions
IDO1 (indoleamine 2, 3-dioxygenase 1) is involved in the metabolism of tryptophan into kynurenine (Kyn) in extrahepatic tissues. It is needed for the first step in the Kyn pathway. IDO1 plays a crucial role in the innate host defenses by suppressing microbial growth. In addition, it enhances the immune tolerance by allowing maturation of naive T lymphocytes into T regulatory cells. It is upregulated in cancer and HIV (human immunodeficiency virus)-disease.
Anti-Indoleamine 2,3-dioxygenase Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-Indoleamine 2,3-dioxygenase Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |