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INT-767

CAS No.
1000403-03-1
Chemical Name:
INT-767
Synonyms
INT-767;INT-767 (INT767)
CBNumber:
CB33048660
Molecular Formula:
C25H45NaO6S
Molecular Weight:
496.68
MDL Number:
MOL File:
1000403-03-1.mol
Last updated:2023-05-21 10:59:17

INT-767 Properties

storage temp. Store at -20°C
solubility DMSO : ≥ 205.5 mg/mL (415.44 mM)

INT-767 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-5007 INT-767 >98.0% 1000403-03-1 5mg $900 2021-12-16 Buy
Biorbyt Ltd orb611413 INT-767 1000403-03-1 5mg $1089.7 2021-12-16 Buy
ChemScene CS-5007 INT-767 >98.0% 1000403-03-1 10mg $1440 2021-12-16 Buy
Biorbyt Ltd orb611413 INT-767 1000403-03-1 10mg $1771.4 2021-12-16 Buy
Biorbyt Ltd orb611413 INT-767 1000403-03-1 25mg $3105.9 2021-12-16 Buy
Product number Packaging Price Buy
CS-5007 5mg $900 Buy
orb611413 5mg $1089.7 Buy
CS-5007 10mg $1440 Buy
orb611413 10mg $1771.4 Buy
orb611413 25mg $3105.9 Buy

INT-767 Chemical Properties,Uses,Production

Description

INT-767 is a G-protein coupled/Farnesoid X-activated receptor agonist potentially for the treatment of hepatic fibrosis. INT-767 significantly improved serum liver enzymes, hepatic inflammation, and biliary fibrosis in Mdr2(-/-) mice. INT-767 significantly induced bile flow and biliary HCO?3- output, as well as gene expression of carbonic anhydrase 14, an important enzyme able to enhance HCO?3- transport, in an Fxr-dependent manner. In addition, INT-767 dramatically reduced bile acid synthesis via the induction of ileal Fgf15 and hepatic Shp gene expression, thus resulting in significantly reduced biliary bile acid output in Mdr2(-/-) mice.

INT-767 Preparation Products And Raw materials

Raw materials

Preparation Products

INT-767 Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29796 68
Musechem +1-800-259-7612 info@musechem.com United States 4662 60
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3069 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19105 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9412 58
INT-767 INT-767 (INT767) 1000403-03-1